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Pregnancy-associated Deaths: 31-year Experience.
Koichi Yoneyama1, Atsuko Sekiguchi, Takashi Matsushima
1Department of Obstetrics and Gynecology, Nippon Medical School Musashi Kosugi Hospital.
Journal of Nippon Medical School = Nippon Ika Daigaku Zasshi
|March 11, 2016
Summary
Pregnancy-associated maternal deaths in Japan were primarily caused by amniotic fluid embolism and hemorrhage. Further research into amniotic fluid embolism is crucial for reducing maternal mortality.
Area of Science:
- Obstetrics and Gynecology
- Maternal Health
- Public Health
Background:
- Pregnancy-associated maternal deaths represent a critical public health concern.
- Understanding the clinical characteristics of these deaths is essential for developing effective prevention strategies.
Purpose of the Study:
- To elucidate the clinical characteristics of pregnancy-associated maternal deaths.
- To identify the leading causes of maternal mortality in Japan.
Main Methods:
- Retrospective analysis of medical records and autopsy reports.
- Inclusion of all maternal deaths related to pregnancy from 1984-2014 at 3 hospitals affiliated with Nippon Medical School, Japan.
- Analysis of maternal age, medical history, gestational age, clinical signs, cause of death, and autopsy findings.
Main Results:
- A total of 26 maternal deaths were recorded over 31 years.
- Amniotic fluid embolism (27.0%) and hemorrhage (23.1%) were the leading causes of direct maternal deaths.
- Indirect causes included cardiovascular and cerebrovascular disorders, and sepsis.
Conclusions:
- Amniotic fluid embolism is the leading cause of maternal deaths in Japan, followed by obstetric hemorrhage.
- Further basic and clinical research on amniotic fluid embolism is required to reduce maternal mortality.
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