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Toxic epidermal necrolysis.

S G Cohen, M Glick, V H Schaeffer

    Special Care in Dentistry : Official Publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry
    |January 1, 1989
    PubMed
    Summary
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    Toxic epidermal necrolysis (TEN) is a severe skin reaction. Early recognition of oral symptoms is crucial for prompt medical intervention in this life-threatening dermatological condition.

    Area of Science:

    • Dermatology
    • Oral Medicine

    Background:

    • Toxic epidermal necrolysis (TEN) is a rare, life-threatening mucocutaneous reaction.
    • It is characterized by widespread epidermal detachment and mucosal involvement.
    • Intraoral lesions can be an early indicator of TEN, preceding skin manifestations.

    Observation:

    • Two distinct cases of toxic epidermal necrolysis are presented.
    • Case details include varying clinical presentations and disease progression.
    • Different treatment strategies were employed for each patient.

    Findings:

    • The study highlights the significance of intraoral manifestations in the early diagnosis of TEN.
    • Treatment outcomes were observed in relation to the applied protocols.
    • The potential for severe skin exfoliation necessitates urgent medical care.

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    Implications:

    • Early identification of oral signs can lead to timely intervention for TEN.
    • Understanding diverse treatment responses is vital for managing this severe dermatological emergency.
    • This case series contributes to the clinical knowledge of TEN management.