Predicting missing links and identifying spurious links via likelihood analysis
Related Experiment Video
Updated: Mar 24, 2026

A Practical Guide to Phylogenetics for Nonexperts
Published on: February 5, 2014
Liming Pan1,2, Tao Zhou2,3, Linyuan Lü1
1Alibaba Research Center for Complexity Sciences, Alibaba Business College, Hangzhou Normal University, Hangzhou 310036, People's Republic of China.
Abstract:
Real network data is often incomplete and noisy, where link prediction algorithms and spurious link identification algorithms can be applied. Thus far, it lacks a general method to transform network organizing mechanisms to link prediction algorithms. Here we use an algorithmic framework where a network's probability is calculated according to a predefined structural Hamiltonian that takes into account the network organizing principles, and a non-observed link is scored by the conditional probability of adding the link to the observed network. Extensive numerical simulations show that the proposed algorithm has remarkably higher accuracy than the state-of-the-art methods in uncovering missing links and identifying spurious links in many complex biological and social networks. Such method also finds applications in exploring the underlying network evolutionary mechanisms.
More Related Videos
07:15Determining the Likelihood of Variant Pathogenicity Using Amino Acid-level Signal-to-Noise Analysis of Genetic Variation
Published on: January 16, 2019
07:08Optimization of Synthetic Proteins: Identification of Interpositional Dependencies Indicating Structurally and/or Functionally Linked Residues
Published on: July 14, 2015
Related Concept Videos
Evolutionary Relationships through Genome Comparisons
Microbial Phylogeny