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Updated: Mar 24, 2026

Generation of Electronic Cigarette Aerosol by a Third-Generation Machine-Vaping Device: Application to Toxicological Studies
Published on: August 25, 2018
Electronic nicotine delivery systems: overheating, fires and explosions
Susan F Rudy1, Elizabeth L Durmowicz2
1Office of Science/Division of Individual Health Science/Medical Branch, United States Food & Drug Administration/Center for Tobacco Products, Silver Spring, Maryland, USA.
Background:
Electronic nicotine delivery system (ENDS)-associated overheating, fire or explosion (OH/F/EXP) events have occurred since at least 2009.
Objective:
To identify the number and nature of ENDS OH/F/EXP events in the USA.
Methods:
Center for Tobacco Products (CTP) scientists searched for event reports among five US federal agencies, scientific literature and media outlets.
Findings:
100 reference sources identified 92 OH/F/EXP events in the USA, of which 45 (49%) injured 47 people, and 67 (73%) involved property damage beyond the product. Events were identified in media outlets (n=50; 54%) and reported to four agencies (n=42; 46%). The report rate peaked at an average of six reports per month in late 2013 with a smaller peak of three to four reports per month in the second quarter of 2015. All reports were incomplete and events exhibited variability. International events in three countries are mentioned, and international responses to events are summarised.
Conclusions:
The scope, causes and trajectory of ENDS OH/F/EXP events remain incompletely defined. Some events have resulted in life-threatening injury, permanent disfigurement or disability, and major property damage, suggesting the need for ongoing surveillance and risk mitigation. More comprehensive reporting could assist future analyses and may help to identify root causes and contributors to the OH/F/EXP events.
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