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Published on: February 28, 2012
[Prevention of venous thromboses with oral anticoagulants]
1Abteilung Angiologie, Johann-Wolfgang-von-Goethe-Universität, Frankfurt, BRD.
Abstract:
Oral anticoagulants are effective for prophylaxis of venous thromboembolism. The therapy is usually monitored by the one-stage prothrombin time (Quicktest). The aim of anticoagulant therapy is to reduce the coagulability of blood into a so called therapeutic range within which the patient is protected against thrombosis while being exposed to a minimal risk of bleeding. The standardization of methods for the prothrombin time assay by the International Normalized Ratio is of further benefit for monitoring the therapy in the individual patient.
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