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Updated: Mar 24, 2026

Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
Efficiency and patient experience with propofol vs conventional sedation: A prospective study
Patrick Thornley1, Mohammad Al Beshir1, James Gregor1
1Patrick Thornley, Michael G. DeGroote School of Medicine, MsMaster University, Hamilton, Ontario L8S 4L8, Canada.
Endoscopist-administered conscious sedation (EAC) with fentanyl/midazolam significantly reduces colonoscopy total room time compared to anaesthesiologist-administered propofol (AAP). Resident participation prolongs procedure time regardless of sedation method.
Area of Science:
- Gastroenterology
- Anesthesiology
- Clinical Medicine
Background:
- Sedation methods impact colonoscopy efficiency and patient experience.
- Anaesthesiologist-administered sedation (AAP) with propofol and endoscopist-administered conscious sedation (EAC) with fentanyl/midazolam are common practices.
Purpose of the Study:
- To compare the duration of colonoscopy and total room time between AAP and EAC.
- To evaluate patient satisfaction and adverse events associated with each sedation method.
Main Methods:
- Prospective, non-randomized comparative study in a Canadian academic endoscopy unit.
- Enrolled 230 adult patients undergoing colonoscopy with either AAP or EAC.
- Assessed patient demographics, procedure data, difficulty, endoscopist level, and patient satisfaction via survey.
Main Results:
- EAC (14.7 min) was associated with shorter mean procedure time than AAP (18.3 min) (P = 0.002).
- Mean total room time was significantly shorter with EAC (30.1 min) compared to AAP (36.8 min) (P < 0.001).
- Resident participation doubled procedure time; AAP was linked to increased total room time, lower pain, and a trend towards higher satisfaction, but had more adverse events.
Conclusions:
- Endoscopist-administered conscious sedation (EAC) is more time-efficient for colonoscopy than anaesthesiologist-administered sedation (AAP).
- Resident involvement significantly increases colonoscopy duration irrespective of sedation type.
- While AAP may reduce pain and improve satisfaction, EAC offers greater efficiency with fewer reported adverse events in this study.
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