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[Bacterial vaginosis].

U B Hoyme1

  • 1Zentrum für Frauenheilkunde am Universitätsklinikum, Essen.

Zentralblatt Fur Gynakologie
|January 1, 1989
PubMed
Summary

Bacterial vaginosis, a common cause of vaginal discharge, results from an imbalanced vaginal microbiome. Diagnosis involves specific symptoms and tests, with nitroimidazoles as the primary treatment.

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S1-Guideline on Bacterial Vaginosis in Gynecology and Obstetrics: Long version - AWMF Guideline, registration no. 015/028, July 2013 Langfassung - AWMF-Register Nr. 015/028, Juli 2013.

Geburtshilfe und Frauenheilkunde·2014
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Prevention of preterm birth is possible by vaginal pH screening, early diagnosis of bacterial vaginosis or abnormal vaginal flora and treatment.

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Intravaginally applied metronidazole is as effective as orally applied in the treatment of bacterial vaginosis, but exhibits significantly less side effects.

European journal of obstetrics, gynecology, and reproductive biology·2008
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[Recurrent uncomplicated urinary tract infection in young woman].

MMW Fortschritte der Medizin·2008
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[Gynaecological and obstetrical aspects of recurrent urinary tract infections].

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Efficient prematurity prevention is possible by pH-self measurement and immediate therapy of threatening ascending infection.

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Area of Science:

  • Gynecology
  • Microbiology
  • Infectious Diseases

Context:

  • Bacterial vaginosis (BV) is the leading cause of vaginal discharge globally.
  • While sexual activity is a risk factor, BV is not a sexually transmitted infection but a disruption of the vaginal ecosystem.
  • BV diagnosis relies on clinical signs like discharge, elevated vaginal pH (>4.5), a positive whiff test, and the presence of clue cells.

Purpose:

  • To outline the key diagnostic criteria for bacterial vaginosis.
  • To identify the preferred therapeutic agents for bacterial vaginosis.
  • To highlight the clinical significance of bacterial vaginosis as a risk factor for other infections.

Summary:

  • Bacterial vaginosis is characterized by an imbalance in the vaginal microbiota, leading to discharge.
  • Diagnostic indicators include vaginal pH, whiff test results, and microscopic identification of clue cells.
  • Oral nitroimidazoles are the recommended first-line treatment for bacterial vaginosis.

Impact:

  • Bacterial vaginosis significantly increases the risk of ascending, postoperative, and perinatal genital infections.
  • Understanding BV's microbiological basis and diagnostic markers is crucial for effective management.
  • Timely diagnosis and treatment of bacterial vaginosis can mitigate associated infectious complications.

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