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Updated: Mar 24, 2026

Author Spotlight: Assessing the Olfactory Effects of Airborne Pollutants — Buried Food and Social Odor Tests
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Does iron deficiency anemia affect olfactory function?

Mehmet Emre Dinc1, Abdullah Dalgic1, Seckin Ulusoy1

  • 1a Department of Otolaryngology, Head and Neck Surgery , Istanbul Gaziosmanpasa Taksim Research and Training Hospital , Istanbul , Turkey.

Acta Oto-Laryngologica
|March 11, 2016
PubMed
Summary
This summary is machine-generated.

Iron-deficiency anemia (IDA) negatively impacts olfactory function, reducing the ability to detect, discriminate, and identify smells. Lower hemoglobin levels in IDA patients further impair smell function.

Keywords:
Iron-deficiency anemiaSniffin’ Sticks olfactory testolfactory function

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Area of Science:

  • Otorhinolaryngology
  • Hematology
  • Neurology

Background:

  • Iron-deficiency anemia (IDA) is a common condition with systemic effects.
  • Olfactory dysfunction can significantly impact quality of life.

Purpose of the Study:

  • To investigate the impact of iron-deficiency anemia (IDA) on olfactory function.
  • To assess specific components of smell, including threshold, discrimination, identification, and selectivity.

Main Methods:

  • The study included 50 patients diagnosed with IDA and 50 healthy controls.
  • Olfactory function was assessed using the validated Sniffin' Sticks test.
  • IDA diagnosis followed World Health Organization (WHO) criteria.

Main Results:

  • IDA patients exhibited significantly lower olfactory threshold, discrimination, and identification (TDI) scores compared to controls.
  • A notable reduction in olfactory threshold was observed in the IDA group.
  • No significant differences were found in smell selectivity between IDA patients and healthy subjects.

Conclusions:

  • Iron-deficiency anemia (IDA) has a detrimental effect on olfactory function.
  • Reduced hemoglobin levels associated with IDA correlate with further declines in olfactory abilities.
  • IDA impacts the overall ability to perceive smells, but not necessarily smell selectivity.