[Research Progress of Quantitative Susceptibility Mapping in MRI]

Area of Science:

• Medical Imaging
• Biophysics
• Magnetic Resonance Imaging (MRI)

Background:

• Magnetic susceptibility quantifies a material's response to an external magnetic field.
• Quantitative susceptibility mapping (QSM) is an MRI technique for in vivo measurement of tissue magnetic susceptibility.
• QSM excels at visualizing paramagnetic and diamagnetic tissue components.

Purpose of the Study:

• To introduce the concept of Quantitative Susceptibility Mapping (QSM).
• To systematically categorize and discuss various QSM methodologies.
• To summarize current research progress and promote QSM's clinical utility.

Main Methods:

• QSM addresses an ill-posed de-convolution problem to generate susceptibility maps.
• Methods include multi-orientation scan-based and single-orientation approaches.
• Review and categorization of existing QSM techniques.

Main Results:

• Multiple QSM methods have been developed to address the ill-posed nature of the problem.
• Both multi-orientation and single-orientation QSM techniques are discussed.
• The paper provides a comprehensive overview of QSM advancements.

Conclusions:

• This review categorizes and discusses various QSM methods.
• The aim is to enhance understanding and promote rational clinical application of QSM.
• Further research and development in QSM are encouraged.