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[THE RELATIONSHIP BETWEEN DISORDERS-OF EXTERNAL RESPIRATION AND RIGHT HEART REMODELING IN PATIENTS WITH ATOPIC
Klinicheskaia Meditsina
|March 12, 2016
Summary
Respiratory issues in bronchial asthma (BA) worsen with disease severity, leading to right heart remodeling and dysfunction. This progression can result in chronic cardiac insufficiency, highlighting a link between airway changes and heart health.
Area of Science:
- Cardiology
- Pulmonology
- Respiratory Medicine
Background:
- Atopic bronchial asthma (BA) is associated with potential cardiovascular complications.
- The interplay between respiratory system state and right heart function in BA requires further elucidation.
Purpose of the Study:
- To evaluate the respiratory system's influence on right heart structure and function in patients with atopic bronchial asthma.
- To optimize diagnostics and prevention strategies for cardiovascular complications in BA patients.
Main Methods:
- Study included 189 subjects: 148 with BA (3 severity groups) and 40 healthy controls.
- Assessed external respiration function and right ventricle functional parameters in all participants.
Main Results:
- External respiration disorders and pulmonary hyperinflation increased with BA severity.
- These respiratory changes promoted right ventricular remodeling and dysfunction.
- Progressive dysfunction led to chronic cardiac insufficiency.
Conclusions:
- Functional changes in the right heart of BA patients correlate with respiratory tract remodeling.
- Severity of BA impacts both respiratory function and right heart health.
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