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Updated: Mar 24, 2026
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Author Spotlight: Advancing Research on Candida albicans Biofilm-Associated Prosthetic Joint Infections
Published on: February 2, 2024
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Prosthetic joint infection caused by Trueperella bernardiae
Raul Gilarranz1, Francisco Chamizo1, Iballa Horcajada1
1Microbiology Department, Hospital Universitario de Gran Canaria Doctor Negrín, Spain.
Summary
Trueperella bernardiae, often a contaminant, can cause prosthetic joint infections. This case highlights its identification via MALDI-TOF and successful treatment with ciprofloxacin, preserving the patient's knee prosthesis.
Area of Science:
- Microbiology
- Infectious Diseases
- Orthopedic Surgery
Background:
- Trueperella bernardiae is a Gram-positive bacterium rarely associated with human infections, often misidentified or considered a contaminant.
- Accurate identification of Trueperella species can be challenging using traditional biochemical methods.
Observation:
- A patient with a history of total knee replacement developed a superinfection and patellar tendon necrosis.
- Synovial fluid analysis revealed a Gram-positive bacilli, later identified as Trueperella bernardiae using MALDI-TOF.
Findings:
- Trueperella bernardiae was identified as the causative agent of a prosthetic joint infection.
- The patient received ciprofloxacin treatment for the infection.
Implications:
- This case expands the known pathogenic potential of Trueperella bernardiae in orthopedic infections.
- Accurate identification using advanced techniques like MALDI-TOF is crucial for effective treatment.
- Successful management with antibiotics preserved the patient's prosthetic joint, avoiding further surgery.
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