Related Experiment Video
Updated: Mar 24, 2026

COVID-19 Seroprevalence Test for IgG Antibody Levels Among Healthy Donors Across Different Pandemic Phases in Jeddah
Published on: June 24, 2025
The Pattern of Juvenile Idiopathic Arthritis in a Single Tertiary Center in Saudi Arabia
Mohammad H Al-Hemairi1, Shatha M Albokhari2, Mohammed A Muzaffer2
1Department of General Pediatrics, Rabigh General Hospital, P.O. Box 51, Rabigh 21911, Saudi Arabia.
Insights
Systemic onset Juvenile Idiopathic Arthritis (JIA) was most common in Saudi children. This study details JIA patient characteristics and treatments in a tertiary center.
Area of Science:
- Pediatric Rheumatology
- Immunology
- Clinical Medicine
Background:
- Juvenile Idiopathic Arthritis (JIA) is the most prevalent chronic arthritis affecting children.
- Understanding JIA's characteristics is crucial for effective management.
Purpose of the Study:
- To characterize the demographic, clinical, and laboratory features of JIA patients.
- To describe treatment patterns for JIA in a Saudi Arabian tertiary center.
Main Methods:
- Retrospective review of medical records for JIA patients from January 2007 to January 2015.
- Data collection included demographics, clinical presentation, laboratory findings, and treatments.
Main Results:
- Systemic onset JIA (SoJIA) was the most frequent subtype (36.5%).
- Large joint involvement (92%) and fever (41.4%) were common; uveitis occurred in 8.5%.
- Anemia (59.7%), elevated ESR (54.8%), and positive ANA (36.5%, especially in oligoarticular JIA) were noted.
Conclusions:
- SoJIA is the predominant JIA subtype in this Saudi cohort.
- Further population-based studies are recommended for a comprehensive understanding of JIA in Saudi Arabia.
Abstract:
Introduction. Juvenile Idiopathic Arthritis (JIA) is the most common chronic arthritis in children. Our aim is to describe demographic, clinical, and laboratory characteristics and treatment of JIA patients followed up in Pediatric Rheumatology clinic in a tertiary center in Saudi Arabia. Methods. Medical records of all patients who are followed up between January 2007 and January 2015 were retrospectively reviewed. Data were collected about demographic, clinical, and laboratory features and treatment. Results. Total patients were 82, males were 31 (37.8%), and mean age of JIA onset was 7.1 ± 3.6 yr. Mean follow-up duration was 2.67±1.6 yr. Systemic onset JIA (SoJIA) was the commonest (36.5%), followed by polyarticular in 29.2% and oligoarticular in 28%. Large and small joints are involved in 76 (92%) and 30 (36.6%), respectively. Main extra-articular feature was fever in 34 (41.4%). Uveitis was diagnosed in 7 (8.5%) and in 5 (21.7%) of oligoarticular JIA. Anemia was found in 49 (59.7%), high ESR in 45 (54.8%), and leukocytosis and thrombocytosis in 33 (40.2%). Positive ANA was found in 30 (36.5%) mainly in oligoarticular subtype as 12 (52%) patients (out of 23) had this positive test. 9 patients (10.9%) required NSAIDs only, 6 patients (7.3%) required NSAIDs and intra-articular steroids only, and 19 (23%) required NSAIDs, methotrexate, steroids, and biologics. Conclusion. SoJIA is the most common JIA subtype in our study. A population based rather than a single center study will give more details about JIA characteristics in Saudi Arabia.
Related Concept Videos
Genome-wide Association Studies-GWAS
GWAS does not require the identification of the target gene involved in...
Knee Joint
A total of seven ligaments support the knee joint. The patellar ligament, which is also attached to the quadriceps femoris...
Rheumatic Heart Disease I: Introduction
Ankle Joint
Development of the Limb Synovial Joints
The mesenchymal stem cells differentiate into chondrocytes that form the hyaline cartilage, and later the cartilaginous model of the bone. This model further transforms into a bone. This process is known as endochondral ossification.
During development, the limbs...
Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies

