Prevention of postoperative seromas with dead space obliteration: A case-control study

Excision of soft tissue masses in the subcutaneous space is a common surgical procedure. Postoperative seromas may occur and often result in additional visits, procedures, and impaired wound healing.

A retrospective chart review (2001-2011) identified patients who underwent resection of a soft tissue mass in the subcutaneous tissues. Patients undergoing breast surgery, head and neck surgery, and lymph node dissections were excluded. Patients (n = 100) with seromas were identified. These patients were matched to patients not having postoperative seroma (n = 100).

We identified 100 patients with seroma and 100 controls without seroma after soft tissue resection. Patients had no difference in wound characteristics. Patients with a dead space obliterating stitch were less likely to have a postoperative seroma (26% vs 74%, P < 0.001).

Dead space closure was associated with a decreased rate of postoperative seroma in subcutaneous resections. Postoperative seroma was associated with increased cost and provider visits.