Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Magnetic Resonance Imaging01:24

Magnetic Resonance Imaging

10.3K
Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
10.3K
Cerebral Hemispheres01:05

Cerebral Hemispheres

3.1K
The human brain, a complex organ, is functionally divided into two cerebral hemispheres—left and right. These hemispheres are interconnected by a structure of paramount importance, the corpus callosum. This substantial bundle of neural fibers is not just a bridge between the hemispheres but a crucial element for the brain's comprehensive functioning. It enables efficient communication between the two hemispheres, allowing each side of the brain to control and receive sensory and motor...
3.1K
Blood Flow01:29

Blood Flow

77.7K
Blood is pumped by the heart into the aorta, the largest artery in the body, and then into increasingly smaller arteries, arterioles, and capillaries. The velocity of blood flow decreases with increased cross-sectional blood vessel area. As blood returns to the heart through venules and veins, its velocity increases. The movement of blood is encouraged by smooth muscle in the vessel walls, the movement of skeletal muscle surrounding the vessels, and one-way valves that prevent backflow.
77.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Distinguishing Molecular and Histologic Glioblastomas Using Multiparametric MRI-Based Habitat Analysis.

Korean journal of radiology·2026
Same author

Distinct spatial patterns of perivascular spaces enlargement for multiple and Co-existing pathologies of cognitive impairment.

The journal of prevention of Alzheimer's disease·2026
Same author

Deep learning algorithm for automatic detection of acute ischemic stroke on noncontrast brain CT.

Scientific reports·2026
Same author

Quantitative multi-echo T2-based cerebrospinal fluid fraction (CSFF) mapping reveals sleep-wake-dependent brain fluid shifts in healthy adults.

AJNR. American journal of neuroradiology·2026
Same author

ROS-Responsive Nanobubbles for Dual-Enhanced Ultrasound and Magnetic Resonance Imaging of Tumor Oxidative Stress.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026
Same author

Physics-Guided Neural Network for Quantitative Parameter Mapping Using Balanced Steady State Free Precession MRI.

Magnetic resonance in medicine·2026

Related Experiment Video

Updated: Mar 24, 2026

Author Spotlight: Noninvasive Cerebral Blood Flow Determination in Human Functional Brain Region for Diagnosis of Neurological Disorders
05:23

Author Spotlight: Noninvasive Cerebral Blood Flow Determination in Human Functional Brain Region for Diagnosis of Neurological Disorders

Published on: May 31, 2024

934

Mapping blood flow directionality in the human brain.

Sung-Hong Park1, Won-Joon Do2, Seung Hong Choi3

  • 1Magnetic Resonance Imaging Laboratory, Department of Bio and Brain Engineering, Korea Advanced Institute of Science and Technology, Daejeon, South Korea; Department of Radiology, University of Pittsburgh, Pittsburgh, PA, United States.

Magnetic Resonance Imaging
|March 13, 2016
PubMed
Summary
This summary is machine-generated.

This study introduces Alternate Ascending/Descending Directional Navigation (ALADDIN) for mapping cerebral blood flow directionality. ALADDIN reveals heterogeneous blood flow directionality in the brain and around tumors, offering new diagnostic insights.

Keywords:
Alternate ascending/descending directional navigationArterial spin labelingBlood flow directionalityBlood flow tensor imagingPerfusion directionalityPerfusion tensor imaging

More Related Videos

Paired Cisterna Magna Nanoinjection and Laser Speckle Contrast Imaging Assay to Study Cerebral Blood Flow Regulation In Vivo
06:24

Paired Cisterna Magna Nanoinjection and Laser Speckle Contrast Imaging Assay to Study Cerebral Blood Flow Regulation In Vivo

Published on: July 8, 2025

1.2K
Cerebral Blood Flow-Based Resting State Functional Connectivity of the Human Brain using Optical Diffuse Correlation Spectroscopy
07:13

Cerebral Blood Flow-Based Resting State Functional Connectivity of the Human Brain using Optical Diffuse Correlation Spectroscopy

Published on: May 27, 2020

7.2K

Related Experiment Videos

Last Updated: Mar 24, 2026

Author Spotlight: Noninvasive Cerebral Blood Flow Determination in Human Functional Brain Region for Diagnosis of Neurological Disorders
05:23

Author Spotlight: Noninvasive Cerebral Blood Flow Determination in Human Functional Brain Region for Diagnosis of Neurological Disorders

Published on: May 31, 2024

934
Paired Cisterna Magna Nanoinjection and Laser Speckle Contrast Imaging Assay to Study Cerebral Blood Flow Regulation In Vivo
06:24

Paired Cisterna Magna Nanoinjection and Laser Speckle Contrast Imaging Assay to Study Cerebral Blood Flow Regulation In Vivo

Published on: July 8, 2025

1.2K
Cerebral Blood Flow-Based Resting State Functional Connectivity of the Human Brain using Optical Diffuse Correlation Spectroscopy
07:13

Cerebral Blood Flow-Based Resting State Functional Connectivity of the Human Brain using Optical Diffuse Correlation Spectroscopy

Published on: May 27, 2020

7.2K

Area of Science:

  • Neuroimaging
  • Biophysics
  • Medical Physics

Background:

  • Diffusion tensor imaging (DTI) captures tissue diffusion directionality.
  • Conventional perfusion-weighted imaging, like arterial spin labeling (ASL), typically provides scalar perfusion values.
  • There is a need for techniques that can map the directional properties of cerebral blood flow.

Purpose of the Study:

  • To evaluate the feasibility of mapping cerebral blood flow directionality using ALADDIN, a novel ASL technique.
  • To assess directional blood flow in vector and tensor forms.
  • To compare blood flow tensor characteristics with time-of-flight MR angiography.

Main Methods:

  • ALADDIN was applied along 3 orthogonal directions to obtain vector blood flow.
  • ALADDIN was used along 6 directions to compute a blood flow tensor matrix (P) based on an ellipsoid model.
  • Tensor elements, including eigenvalues and eigenvectors, were calculated and analyzed.

Main Results:

  • Heterogeneous cerebral blood flow directionality was observed across the brain.
  • Reproducible regional clusters of blood flow directionality were identified.
  • Distinct blood flow directionality patterns were found within and around brain tumors compared to normal tissue.

Conclusions:

  • ALADDIN enables the mapping of cerebral blood flow directionality, a novel capability.
  • The technique demonstrates potential for characterizing heterogeneous flow patterns in conditions like brain tumors.
  • Further research is warranted to optimize parameters, understand signal origins, and explore clinical utility.