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Characterization of insulin-degrading enzyme-mediated cleavage of Aβ in distinct aggregation states

Ellen Hubin1, Federica Cioffi2, Jef Rozenski3

  • 1Nanobiophysics Group, MIRA Institute for Biomedical Technology and Technical Medicine, Faculty of Science and Technology, Universiteit Twente, Enschede, The Netherlands; Structural Biology Brussels, Vrije Universiteit Brussel, Pleinlaan 2, 1050 Brussels, Belgium; Structural Biology Research Center, VIB, Pleinlaan 2, 1050 Brussels, Belgium.

Biochimica Et Biophysica Acta
|March 13, 2016
PubMed

Keywords:
AggregationAlzheimer's diseaseAmyloid-betaAβ cleavageInsulin-degrading enzymeNeprilysin

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