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From a Natural Product to Its Biosynthetic Gene Cluster: A Demonstration Using Polyketomycin from Streptomyces diastatochromogenes Tü6028
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Enhanced salinomycin production by adjusting the supply of polyketide extender units in Streptomyces albus

Chenyang Lu1, Xiaojie Zhang1, Ming Jiang1

  • 1State Key Laboratory of Microbial Metabolism and School of Life Sciences & Biotechnology, Shanghai Jiaotong University, Shanghai 200240, China; Joint International Research Laboratory of Metabolic & Developmental Sciences, Shanghai Jiao Tong University, Shanghai 200240, China.

Metabolic Engineering
|March 13, 2016
PubMed

Keywords:
Crotonyl-CoA reductaseExtender unitGenomePolyketideSalinomycin

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