Jove
Visualize
Contact Us

Related Concept Videos

Gastrulation01:56

Gastrulation

68.8K
Gastrulation establishes the three primary tissues of an embryo: the ectoderm, mesoderm, and endoderm. This developmental process relies on a series of intricate cellular movements, which in humans transforms a flat, “bilaminar disc” composed of two cell sheets into a three-tiered structure. In the resulting embryo, the endoderm serves as the bottom layer, and stacked directly above it is the intermediate mesoderm, and then the uppermost ectoderm. Respectively, these tissue strata...
68.8K
Neurulation01:30

Neurulation

47.2K
Neurulation is the embryological process which forms the precursors of the central nervous system and occurs after gastrulation has established the three primary cell layers of the embryo: ectoderm, mesoderm, and endoderm. In humans, the majority of this system is formed via primary neurulation, in which the central portion of the ectoderm—originally appearing as a flat sheet of cells—folds upwards and inwards, sealing off to form a hollow neural tube. As development proceeds, the...
47.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Wnt dynamics at the blastopore and stomodeum during sea urchin gastrulation.

Development (Cambridge, England)·2026
Same author

Author Correction: A molecular basis for spine color morphs in the sea urchin Lytechinus variegatus.

Scientific reports·2025
Same author

Reprogramming of cells during embryonic transfating: overcoming a reprogramming block.

Development (Cambridge, England)·2024
Same author

Single-Cell Transcriptomics Reveals Evolutionary Reconfiguration of Embryonic Cell Fate Specification in the Sea Urchin Heliocidaris erythrogramma.

Genome biology and evolution·2024
Same author

A molecular basis for spine color morphs in the sea urchin Lytechinus variegatus.

Scientific reports·2024
Same author

Contrasting the development of larval and adult body plans during the evolution of biphasic lifecycles in sea urchins.

Development (Cambridge, England)·2024
Same journal

Building a resilient ovarian reserve: Early soma-oocyte interactions.

Current topics in developmental biology·2026
Same journal

Role of macrophages in testis function.

Current topics in developmental biology·2026
Same journal

Role of retinoic acid in meiosis.

Current topics in developmental biology·2026
Same journal

Impact of cancer immunotherapies on oocyte health and ovarian function.

Current topics in developmental biology·2026
Same journal

The ovarian stroma as a key regulator of follicular development and gamete quality across the reproductive lifespan.

Current topics in developmental biology·2026
Same journal

Intercellular cyclic nucleotide dynamics mediate oocyte meiosis in mammalian preovulatory follicles.

Current topics in developmental biology·2026
See all related articles
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Mar 24, 2026

The Power of Simplicity: Sea Urchin Embryos as in Vivo Developmental Models for Studying Complex Cell-to-cell Signaling Network Interactions
07:34

The Power of Simplicity: Sea Urchin Embryos as in Vivo Developmental Models for Studying Complex Cell-to-cell Signaling Network Interactions

Published on: February 16, 2017

8.5K

Sea Urchin Morphogenesis.

David R McClay1

  • 1Department of Biology, Duke University, Durham, North Carolina, USA.

Current Topics in Developmental Biology
|March 13, 2016
PubMed
Summary
This summary is machine-generated.

Sea urchin development involves extensive molecular specification before morphogenesis and patterning. Discoveries over 50 years reveal gene regulatory networks controlling skeletal development and patterning signals from ectoderm.

Keywords:
Gene regulatory networksMorphogenesisSea urchinSkeletogenesis

More Related Videos

High Throughput Microinjections of Sea Urchin Zygotes
12:40

High Throughput Microinjections of Sea Urchin Zygotes

Published on: January 21, 2014

15.2K
A Protocol for Bioinspired Design: A Ground Sampler Based on Sea Urchin Jaws
09:10

A Protocol for Bioinspired Design: A Ground Sampler Based on Sea Urchin Jaws

Published on: April 24, 2016

11.8K

Related Experiment Videos

Last Updated: Mar 24, 2026

The Power of Simplicity: Sea Urchin Embryos as in Vivo Developmental Models for Studying Complex Cell-to-cell Signaling Network Interactions
07:34

The Power of Simplicity: Sea Urchin Embryos as in Vivo Developmental Models for Studying Complex Cell-to-cell Signaling Network Interactions

Published on: February 16, 2017

8.5K
High Throughput Microinjections of Sea Urchin Zygotes
12:40

High Throughput Microinjections of Sea Urchin Zygotes

Published on: January 21, 2014

15.2K
A Protocol for Bioinspired Design: A Ground Sampler Based on Sea Urchin Jaws
09:10

A Protocol for Bioinspired Design: A Ground Sampler Based on Sea Urchin Jaws

Published on: April 24, 2016

11.8K

Area of Science:

  • Developmental Biology
  • Molecular Biology
  • Marine Biology

Background:

  • Sea urchin development proceeds through molecular specification, controlling morphogenesis and larval body plan patterning.
  • Historical research established phenomenological aspects of skeletal morphogenesis before molecular components were known.

Purpose of the Study:

  • To present the historical sequence of discoveries in sea urchin development over the last 50 years.
  • To outline the molecular mechanisms underlying specification, morphogenesis, and patterning in sea urchin larvae.

Main Methods:

  • Review of experimental studies and discoveries in sea urchin development.
  • Analysis of transcription factors, signals, and proteins involved in skeletal development.
  • Perturbation experiments to model gene regulatory networks and signaling pathways.

Main Results:

  • Identification of key transcription factors and signals essential for specification, morphogenesis, and patterning.
  • Development of models for gene regulatory networks governing early development.
  • Understanding that ectoderm signals pattern skeletogenic cells, which secrete a patterned skeleton.

Conclusions:

  • Significant progress has been made in understanding sea urchin skeletal development through molecular tools.
  • Ectoderm-derived signals play a crucial role in patterning skeletogenic cells.
  • Further research is needed to fully elucidate signal complexity and genotypic control of skeletal biomineralization.