Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Psychosurgery01:30

Psychosurgery

2.2K
Psychosurgery, the surgical alteration or permanent removal of brain tissue to alleviate severe psychological conditions, stands as one of the most radical and controversial treatments in the history of mental health care. Its development and application have evolved significantly, marked by dramatic shifts in scientific understanding and ethical perspectives.
Historical Development of Psychosurgery
In the 1930s, Portuguese neurologist Antonio Egas Moniz introduced a surgical procedure designed...
2.2K
Psychosis: Pathophysiology of Schizophrenia and Other Psychotic Disorders01:27

Psychosis: Pathophysiology of Schizophrenia and Other Psychotic Disorders

2.4K
Schizophrenia is a neurodevelopmental disorder whose origins are rooted in complex genetic components. Despite our burgeoning understanding, the pathophysiology of this disorder remains incompletely deciphered.
Researchers have identified genetic factors that increase susceptibility to schizophrenia, underscoring the intricate interplay between genetics and environment in disease development. At the core of schizophrenia's pathophysiology is excessive dopaminergic neurotransmission within...
2.4K
Biological Causes of Schizophrenia01:29

Biological Causes of Schizophrenia

997
Schizophrenia, a severe psychiatric disorder, arises from a complex interplay of biological factors, including genetic predisposition, structural brain abnormalities, neurotransmitter dysregulation, and developmental irregularities. These factors collectively contribute to the onset and progression of the disorder, which typically manifests in late adolescence or early adulthood.
Genetic Factors in Schizophrenia
The genetic basis of schizophrenia is strongly supported by family and twin...
997
Psychological and Sociocultural Causes of Schizophrenia01:29

Psychological and Sociocultural Causes of Schizophrenia

829
Schizophrenia, a complex psychiatric disorder, has been historically misunderstood. Early psychological theories attributed its origins to childhood trauma and unresponsive parenting. However, contemporary research largely rejects these notions, favoring the vulnerability-stress hypothesis. This model proposes that individuals with a genetic predisposition to schizophrenia may develop the disorder following exposure to significant environmental stressors. Notably, studies on high-risk...
829
The Scientific Method02:40

The Scientific Method

67.0K
Research is what makes the difference between facts and opinions. Facts are observable realities, and opinions are personal judgments, conclusions, or attitudes that may or may not be accurate. In the scientific community, facts can be established only using evidence collected through empirical research.
67.0K
Psychology as a Science01:13

Psychology as a Science

4.2K
Psychology, as a scientific discipline, aims to understand the mind and behavior through rigorous and systematic methods. The foundation of psychological research is evidence-based, relying heavily on the scientific method to derive and validate knowledge. This structured approach ensures that findings are reliable, valid, and applicable to broader contexts.
The scientific method in psychology involves six critical steps: making observations, formulating hypotheses, conducting tests, analyzing...
4.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

La casa de papel: A pandemic in a pandemic.

Journal of affective disorders·2020
Same author

When and how to use lithium.

Acta psychiatrica Scandinavica·2020
Same author

Digital depression: a new disease of the millennium?

Acta psychiatrica Scandinavica·2020
Same author

Putting Codman's lesson to work: measuring and improving the quality of Italian mental health care.

Acta psychiatrica Scandinavica·2019
Same author

Updates in treating comorbid bipolar disorder and obsessive-compulsive disorder: A systematic review.

Journal of affective disorders·2019
Same author

Aripiprazole augmentation in treating comorbid bipolar disorder and obsessive-compulsive disorder: A systematic review.

Journal of affective disorders·2019
Same journal

Serum Levels of IFN-γ and NGF as Potential Biomarkers of Depressive Disorders.

Acta neuropsychiatrica·2026
Same journal

The Danish Region Midt Schizophrenia Cohort - Representative, long-term follow-up of first-episode schizophrenia spectrum disorder.

Acta neuropsychiatrica·2026
Same journal

The effects of psychedelics on attention deficit and hyperactivity disorder - a systematic review.

Acta neuropsychiatrica·2026
Same journal

Breaking down the ADHD construct to build a valid diagnosis.

Acta neuropsychiatrica·2026
Same journal

A comprehensive systematic review of human trials investigating herbal treatments for Alzheimer's disease and dementia.

Acta neuropsychiatrica·2026
Same journal

Age-dependent increase in peripheral neuropeptide Y with no cross-sectional link to depression.

Acta neuropsychiatrica·2026
See all related articles

Related Experiment Video

Updated: Mar 24, 2026

Developing a Rat Model for Bipolar Disorder
04:42

Developing a Rat Model for Bipolar Disorder

Published on: May 2, 2025

1.6K

Prospects for a scientific psychiatry.

F K Goodwin, S N Ghaemi

    Acta Neuropsychiatrica
    |March 15, 2016
    PubMed
    Summary
    This summary is machine-generated.

    Psychiatric diagnosis needs patient insights, moving beyond current criteria. Advances in psychopharmacology, like lithium, are key to improving psychiatric nosology and treatment.

    More Related Videos

    Olfactory Neurons Obtained through Nasal Biopsy Combined with Laser-Capture Microdissection: A Potential Approach to Study Treatment Response in Mental Disorders
    08:33

    Olfactory Neurons Obtained through Nasal Biopsy Combined with Laser-Capture Microdissection: A Potential Approach to Study Treatment Response in Mental Disorders

    Published on: December 4, 2014

    10.2K
    Implementation of a Real-Time Psychosis Risk Detection and Alerting System Based on Electronic Health Records using CogStack
    07:31

    Implementation of a Real-Time Psychosis Risk Detection and Alerting System Based on Electronic Health Records using CogStack

    Published on: May 15, 2020

    8.2K

    Related Experiment Videos

    Last Updated: Mar 24, 2026

    Developing a Rat Model for Bipolar Disorder
    04:42

    Developing a Rat Model for Bipolar Disorder

    Published on: May 2, 2025

    1.6K
    Olfactory Neurons Obtained through Nasal Biopsy Combined with Laser-Capture Microdissection: A Potential Approach to Study Treatment Response in Mental Disorders
    08:33

    Olfactory Neurons Obtained through Nasal Biopsy Combined with Laser-Capture Microdissection: A Potential Approach to Study Treatment Response in Mental Disorders

    Published on: December 4, 2014

    10.2K
    Implementation of a Real-Time Psychosis Risk Detection and Alerting System Based on Electronic Health Records using CogStack
    07:31

    Implementation of a Real-Time Psychosis Risk Detection and Alerting System Based on Electronic Health Records using CogStack

    Published on: May 15, 2020

    8.2K

    Area of Science:

    • Psychiatry
    • Neuroscience
    • Pharmacology

    Background:

    • Herman van Praag's significant contributions to psychiatric science.
    • Current diagnostic criteria lack patient subjective experience, leading to 'coarsening of diagnosis'.
    • Weakening of the nosologic infrastructure in scientific psychiatry.

    Purpose of the Study:

    • To discuss the limitations of current psychiatric diagnostic systems.
    • To highlight the importance of incorporating patient subjective experiences.
    • To emphasize the role of psychopharmacology in advancing psychiatry.

    Main Methods:

    • Conceptual analysis of psychiatric nosology.
    • Review of diagnostic criteria and their limitations.
    • Exploration of psychopharmacology's impact on psychiatric advancement.

    Main Results:

    • Current diagnostic systems oversimplify complex patient experiences.
    • A 'coarsening of diagnosis' has resulted from ignoring subjective insights.
    • Psychopharmacology offers a path toward a more refined psychiatric nosology.

    Conclusions:

    • Integrating patient subjective experiences is crucial for accurate psychiatric diagnosis.
    • Psychopharmacology, exemplified by lithium, is central to advancing psychiatric nosology.
    • Refining diagnostic criteria requires a deeper understanding of patient illness experiences.