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Remote Limb Ischemic Preconditioning: A Neuroprotective Technique in Rodents
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Ischemic Conditioning: Implications for Emergency Medicine
Kenneth Frumkin1, Adam S Bloom1
1Emergency Medicine Department, Naval Medical Center, Portsmouth, VA.
Abstract:
Ischemic conditioning refers to the ability of brief episodes of controlled hypoperfusion around the time of an acute ischemic event to protect the target organ from reperfusion injury. A considerable body of literature suggests that interventions as simple and safe as repetitively inflating a blood pressure cuff could reduce the size and long-term morbidity of myocardial and cerebral infarction. This review introduces and summarizes the body of evidence contributing to these impressions.
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