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Bacteremia Caused by Raoultella ornithinolytica in Two Children

Kiyoshi Yamakawa1, Yuka Yamagishi, Kenji Miyata

  • 1From the *Department of Pediatrics, †Department of Clinical Infectious Diseases, Aichi Medical University School of Medicine, Nagakute, Aichi, Japan.

The Pediatric Infectious Disease Journal
|March 15, 2016
PubMed

Insights

Two immunocompromised children developed Raoultella ornithinolytica bacteremia. Prompt antibiotic treatment led to successful recovery in both cases, highlighting effective management strategies for this rare infection.

Area of Science:

  • Pediatric Infectious Diseases
  • Microbiology
  • Immunocompromised Host Research

Background:

  • Raoultella ornithinolytica is an emerging Gram-negative bacterium that can cause opportunistic infections.
  • Immunocompromised children, particularly those with hematologic malignancies or undergoing immunosuppressive therapy, are at increased risk for severe bacterial infections.

Observation:

  • Two pediatric cases of Raoultella ornithinolytica bacteremia are presented.
  • One patient had IgA nephropathy treated with methylprednisolone, and the other had chemotherapy-induced leukopenia for leukemia.
  • Both children presented with non-specific symptoms, with bacteremia detected via routine blood cultures.

Findings:

  • Raoultella ornithinolytica bacteremia can occur in immunocompromised children without specific clinical signs.
  • Diagnosis was established through standard blood cultures.
  • Both patients responded well to appropriate antibiotic therapy.

Implications:

  • This case series expands the understanding of Raoultella ornithinolytica as a potential pathogen in pediatric immunocompromised populations.
  • Early detection via routine blood cultures and prompt antibiotic intervention are crucial for favorable outcomes.
  • Further research into the epidemiology and virulence factors of Raoultella ornithinolytica in vulnerable pediatric groups is warranted.

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