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The effect of shift work on gastrointestinal (GI) function: a review.
K J Vener1, S Szabo, J G Moore
1National Institute of Arthritis, Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, Maryland.
Chronobiologia
|October 1, 1989
Summary
Shift work affects 20% of American workers and increases gastrointestinal disease risk. Disrupted body rhythms and central nervous system changes likely contribute to these shiftwork-related digestive issues.
Area of Science:
- Occupational Health
- Gastroenterology
- Chronobiology
Background:
- Approximately 20% of the American workforce engages in shift work.
- Shift work is increasingly recognized as a potential risk factor for various health issues.
- Gastrointestinal complaints are frequently reported by individuals working non-traditional hours.
Purpose of the Study:
- To review the evidence linking shift work to gastrointestinal diseases or disorders.
- To explore the potential mechanisms underlying shiftwork-related gastrointestinal complaints.
- To discuss the role of circadian rhythm disruption in the pathogenesis of these conditions.
Main Methods:
- Literature review of existing studies on shift work and gastrointestinal health.
- Analysis of epidemiological data and clinical observations.
- Discussion of neuroendocrine pathways involved in digestive regulation.
Main Results:
- Evidence suggests a significant association between shift work and an increased risk of gastrointestinal diseases.
- Disruption of the body's natural time structure (circadian rhythm) appears to be a key factor.
- Central nervous system and endocrine system dysregulations are implicated in the development of these disorders.
Conclusions:
- Shift workers are demonstrably at higher risk for developing gastrointestinal problems.
- The disruption of circadian rhythms is a primary mechanism contributing to these health risks.
- Further research into neuroendocrine factors is warranted to understand and mitigate these effects.