Related Experiment Video

Updated: Mar 24, 2026

Developing a Rat Model for Bipolar Disorder
04:42

Developing a Rat Model for Bipolar Disorder

Published on: May 2, 2025

1.6K

Pediatric mania: a developmental subtype of bipolar disorder?

J Biederman1, E Mick1, S V Faraone1

  • 1Pediatric Psychopharmacology Unit,Massachusetts General Hospital and Harvard Medical School,Boston,U.S.A.

Acta Neuropsychiatrica
|March 16, 2016
PubMed

Insights

Pediatric mania, though controversial, is increasingly recognized as not rare but difficult to diagnose. Early identification of childhood-onset mania is crucial for understanding bipolar disorder subtypes.

Area of Science:

  • Child and Adolescent Psychiatry
  • Neurodevelopmental Disorders
  • Mental Health Research

Background:

  • The prevalence and existence of pediatric mania remain debated.
  • Previous views suggested pediatric mania is rare or non-existent.
  • Recent systematic research challenges these traditional perspectives.

Purpose of the Study:

  • To challenge the notion that pediatric mania is rare.
  • To highlight the diagnostic challenges associated with pediatric mania.
  • To underscore the importance of identifying childhood-onset mania for understanding bipolar disorder.

Main Methods:

  • Review of systematic research and case reports on pediatric mania.
  • Analysis of diagnostic complexities in children.
  • Examination of comorbidity patterns and treatment responses.

Main Results:

  • Pediatric mania may not be rare but is often difficult to diagnose.
  • Unique comorbidities in children include ADHD, aggression, conduct disorder, and substance use disorders.
  • Association with trauma and atypical treatment responses complicate diagnosis.

Conclusions:

  • Childhood-onset mania is a significant clinical entity.
  • Recognizing pediatric mania is vital for identifying potential bipolar disorder subtypes.
  • Further investigation into the unique characteristics of pediatric mania is warranted.

More Related Videos

EEG Mu Rhythm in Typical and Atypical Development11:50

EEG Mu Rhythm in Typical and Atypical Development

Published on: April 9, 2014

26.7K
Handwriting Analysis Indicates Spontaneous Dyskinesias in Neuroleptic Naïve Adolescents at High Risk for Psychosis05:52

Handwriting Analysis Indicates Spontaneous Dyskinesias in Neuroleptic Naïve Adolescents at High Risk for Psychosis

Published on: November 21, 2013

15.6K

Related Concept Videos

Bipolar Disorder01:30

Bipolar Disorder

Bipolar disorder is a chronic mental health condition marked by significant mood fluctuations, including episodes of mania and depression. Elevated energy levels, heightened mood or irritability, impulsive behavior, reduced sleep needs, rapid speech, racing thoughts, inflated self-esteem, and distractibility characterize mania. Individuals with bipolar disorder often alternate between depressive and manic states, with periods of emotional stability lasting an average of six months to a year.
1.3K
Mania and Antimanic Drugs: Overview01:24

Mania and Antimanic Drugs: Overview

Mania, a psychological condition characterized by elevated mood, increased energy, and reduced sleep need, is part of the bipolar disorder cycle. The exact cause of mania isn't entirely known, but it is thought to be a combination of genetic, environmental, and neurological factors. Bipolar disorder involves alternating manic and depressive episodes. Mood stabilizers like lithium, antipsychotics, and anticonvulsants help manage these episodes. Lithium carbonate is particularly effective as...
756
Oppositional Defiant Disorder01:30

Oppositional Defiant Disorder

A persistent pattern of angry or irritable mood, defiant behavior, or vindictiveness characterizes Oppositional Defiant Disorder (ODD). Symptoms must occur over at least six months, involve interactions with individuals beyond siblings, and meet specific diagnostic criteria to be clinically significant. The disorder affects emotional regulation, social interactions, and behavior, often manifesting early in life and influencing long-term development and functioning.
Diagnostic Criteria and...
1.3K
Borderline Personality Disorder01:25

Borderline Personality Disorder

Borderline Personality Disorder is a complex and multifaceted mental health condition characterized by pervasive instability in interpersonal relationships, self-image, emotions, and impulse control. This instability manifests in extreme emotional reactions, fear of abandonment, and self-destructive behaviors. The disorder significantly impacts daily functioning, often leading to distress in both personal and professional domains.
Genetic and Environmental Contributions
Borderline Personality...
882
Attention-Deficit/Hyperactivity Disorder01:30

Attention-Deficit/Hyperactivity Disorder

Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by persistent inattention, hyperactivity, and impulsivity. It affects approximately 5-8% of children globally, with around 60-70% of cases persisting into adulthood. ADHD has significant implications for educational attainment, social interactions, and occupational success.
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings....
1.3K
Conduct Disorder01:28

Conduct Disorder

Conduct disorder is a complex mental health diagnosis characterized by a repetitive and persistent pattern of behavior that violates societal norms, the rights of others, or age-appropriate rules. The diagnostic criteria for conduct disorder require the presence of at least three problematic behaviors within the past 12 months, with at least one occurring in the past six months. These behaviors are grouped into four categories: aggression toward people and animals; destruction of property;...
828