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Phenotypic features of chronic migraine
Osman Özgür Yalın1, Derya Uluduz2, Aynur Özge3
1Neurology Department, Istanbul Education and Research Hospital, Kasap İlyas Mah. Org. Abdurrahman, Nafiz Gürman Cd, PK: 34098, Fatih, Istanbul, Turkey. osmanozguryalin@yahoo.com.
The Journal of Headache and Pain
|March 16, 2016
Summary
Chronic migraine patients often experience accompanying symptoms like phonophobia and nausea. However, increased headache frequency correlated inversely with these symptoms, suggesting a complex relationship in chronic migraine.
Area of Science:
- Neurology
- Headache Medicine
Background:
- Chronic migraine is a significant health burden, often underdiagnosed and undertreated.
- Understanding its phenotypic features is crucial for effective management.
Purpose of the Study:
- To evaluate the phenotypic characteristics of chronic migraine.
- To determine the relevance of accompanying symptoms in chronic migraine attacks.
Main Methods:
- Retrospective analysis of 835 chronic migraine patients from the Turkish Headache Database Study.
- Examination of clinical characteristics, including accompanying symptoms and their relation to migraine features.
Main Results:
- Phonophobia, nausea, and photophobia were the most frequent accompanying symptoms.
- Increased headache frequency showed an inverse relationship with nausea, vomiting, phonophobia, and photophobia.
- Osmophobia was frequent (53.4%) and associated with other symptoms, unlike vertigo and dizziness.
Conclusions:
- Phenotype of chronic migraine is linked to its chronification process.
- Illness duration and attack intensity correlate with accompanying symptoms, while headache frequency shows an inverse relation.
- Including osmophobia in diagnostic criteria could enhance accurate chronic migraine diagnosis.
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