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Multiple vertebral fractures in young man as first manifestation of systemic mastocytosis
Carmen Carrasco Cubero1, Eugenio Chamizo Carmona2
1Servicio de Reumatología, Complejo Hospitalario Universitario de Badajoz, Hospital Perpetuo Socorro, Badajoz, España.
Abstract:
Systemic mastocytosis (SM) is a clonal disease of mast cell progenitors from the bone marrow. The clinical picture varies from asymptomatic forms (indolent) to a highly aggressive form with a very short (mast cell leukemia) survival. Between 28-34% of patients with SM are related to bone condition at the time of diagnosis and 16% have symptomatic fractures. The presentation of SM as clinical vertebral fractures in young men is rare. Here, we describe a case of established osteoporosis as the only manifestation of SM.
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