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Primary Hepatic Carcinoid Tumor with Poor Outcome
Om Parkash1, Adil Ayub2, Buria Naeem2
1Department of Medicine, The Aga Khan University Hospital, Karachi.
Summary
Primary Hepatic Carcinoid Tumors (PHCT) are rare, but late diagnosis leads to poor outcomes. Early detection and surgical resection are crucial for curative treatment of this neuroendocrine tumor.
Area of Science:
- Hepatology
- Oncology
- Endocrinology
Background:
- Primary Hepatic Carcinoid Tumors (PHCT) are exceptionally rare neuroendocrine neoplasms originating in the liver.
- Surgical resection is typically curative for PHCT, with infrequent metastasis.
- This report highlights challenges in diagnosing and managing PHCT.
Observation:
- Two cases of PHCT presented with non-specific symptoms at advanced stages.
- One patient had a 2-week symptomatic history; the other had a 2-year undiagnosed interval.
- Both patients experienced poor outcomes attributed to delayed diagnosis.
Findings:
- Both cases were diagnosed with primary hepatic carcinoid tumors.
- Case 1 received palliative care and expired within one month.
- Case 2 was advised surgical resection but left against medical advice.
Implications:
- Emphasizes the critical need for timely diagnosis of rare liver tumors.
- Underscores the importance of thorough workup for persistent, non-specific symptoms.
- Highlights potential challenges in patient adherence to treatment recommendations for PHCT.

