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Pleomorphous leiomyosarcoma of the mesocolon: a case report
Saad Rifki Jai1, Robleh Hassan Farah1, Brahim Hamdaoui1
1Service de Chirurgie Viscérale Aile 3, Centre Hospitalier Universitaire Ibn Rochd, Université Hassan II, Casablanca, Maroc.
The Pan African Medical Journal
|March 16, 2016
Summary
Leiomyosarcoma, a rare smooth muscle tumor, can occur in the mesocolon, posing diagnostic challenges. Surgical intervention remains the primary treatment for this uncommon gastrointestinal sarcoma.
Area of Science:
- Gastroenterology
- Surgical Oncology
- Pathology
Background:
- Leiomyosarcoma is a rare smooth muscle tumor, frequently found in the stomach and small intestine.
- Mesocolic leiomyosarcoma is exceptionally rare, accounting for less than 0.1% of malignant colon and anal tumors globally.
- Differential diagnosis is challenging due to similarities with other mesenchymal or benign smooth muscle tumors.
Observation:
- This report details a rare case of leiomyosarcoma originating in the mesocolon.
- The diagnostic difficulty, even at the histological level, is highlighted.
- The case underscores the rarity of this specific tumor location.
Findings:
- Leiomyosarcoma diagnosis can be complex, requiring careful histological evaluation.
- Surgical resection is the principal therapeutic approach for leiomyosarcoma.
- The mesocolon is an unusual site for leiomyosarcoma, making it a distinct pathological entity.
Implications:
- Increased awareness of mesocolic leiomyosarcoma is crucial for timely diagnosis and treatment.
- Further research into diagnostic markers and therapeutic strategies for rare leiomyosarcomas is warranted.
- This case contributes to the understanding of rare gastrointestinal stromal tumors and their management.

