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Progress and prospects of long noncoding RNAs in lipid homeostasis
1School of Life Sciences, Northeast Normal University, Changchun, Jilin 130024, China.
Background:
Long noncoding RNAs (lncRNAs) are a novel group of universally present, non-coding RNAs (>200 nt) that are increasingly recognized as key regulators of many physiological and pathological processes.
Scope Of Review:
Recent publications have shown that lncRNAs influence lipid homeostasis by controlling lipid metabolism in the liver and by regulating adipogenesis. lncRNAs control lipid metabolism-related gene expression by either base-pairing with RNA and DNA or by binding to proteins.
Major Conclusions:
The recent advances and future prospects in understanding the roles of lncRNAs in lipid homeostasis are discussed.
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