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Congenital and developmental cataracts and multimalformation syndromes
A M Bardelli1, G Lasorella, M Vanni
1Cattedra di Oftalmologia Pediatrica, Università di Siena, Italy.
Ophthalmic Paediatrics and Genetics
|December 1, 1989
Summary
Cataracts can develop at any age and are frequently linked to various systemic disorders, including genetic conditions. The exact causes of many cataract-associated syndromes remain unknown.
Area of Science:
- Ophthalmology
- Genetics
- Systemic Diseases
Background:
- Cataracts are a significant cause of visual impairment.
- They can be congenital or develop later in life.
- Cataracts are associated with numerous systemic conditions.
Purpose of the Study:
- To review the association between cataracts and systemic disorders.
- To highlight the diverse range of associated conditions.
- To discuss the etiological uncertainty in many cases.
Main Methods:
- Literature review of studies on cataracts and systemic disorders.
- Analysis of reported associations with congenital and acquired cataracts.
- Examination of genetic and unknown causes of associated syndromes.
Main Results:
- Cataracts are linked to connective tissue disorders.
- Neurological conditions, chromosomal abnormalities, and dermatological disorders are also associated.
- Many associated syndromes have an uncertain hereditary basis or unknown etiology.
Conclusions:
- Cataract formation is complex and often multifactorial.
- Systemic health significantly impacts ocular health, specifically cataract development.
- Further research is needed to elucidate the causes of many cataract-associated syndromes.