[Characteristics of risk factors in young and middle-aged patients with first hemispheric ischemic stroke]
A A Kvetkovskaya1, M E Evsev'eva1, M Yu Martynov2
1Stavropolsky State Medical University, Stavropol.
Insights
Risk factors for first ischemic stroke differ significantly across age groups. Young and middle-aged individuals show more blood pressure variability and stress-related factors, while older adults have different profiles, necessitating tailored prevention strategies.
Area of Science:
- Neurology
- Cardiology
- Epidemiology
Context:
- First hemispheric ischemic stroke presents unique challenges in risk factor identification.
- Understanding age-specific risk factors is crucial for effective stroke prevention.
Purpose:
- To compare the risk factors associated with the first hemispheric ischemic stroke across young, middle-aged, and elderly patient groups.
- To identify age-related differences in the prevalence and characteristics of stroke risk factors.
Summary:
- A study of 113 first-time ischemic stroke patients revealed distinct risk factor profiles based on age.
- Younger and middle-aged patients exhibited higher rates of blood pressure variability, emotional stress, family history of cardiovascular disease, lower HDL levels, and minor cardiac abnormalities compared to older patients.
- Advanced-aged patients presented a different spectrum of risk factors, highlighting age-specific vulnerabilities.
Impact:
- Findings underscore the importance of age-tailored stroke prevention programs.
- This research can inform clinical practice by guiding risk assessment and intervention strategies for diverse age demographics.
- Highlights the need for personalized approaches in managing cerebrovascular disease risk.
Aim:
To compare risk factors of the first hemispheric ischemic stroke in young, middle and old age groups.
Material And Methods:
One hundred and thirteen patients with first hemispheric ischemic stroke confirmed by CT/MRI were examined. The patients were divided into 2 groups: young and middle-aged (51 patients, 24 women, 27 men, mean age 49.8±5.2) and advanced-aged (62 patients, 30 women, 32 men, mean age 76.4±7.5). The frequency and duration of the following risk factors for ischemic stroke, including arterial hypertension, ischemic heart disease and arrhythmias, diabetes, smoking, family history of myocardial infarction and/or stroke, body mass index, acute emotional stress before the onset of the disease, were compared. Results of echocardiography, Holter and blood pressure monitoring, total cholesterol, low and high-density lipoproteins, triglycerides and blood glucose were analyzed.
Results:
In young and middle-aged patients, an increased variability of blood pressure, acute emotional stress before the onset of stroke, a family history of cardiovascular and/or cerebrovascular disease, a decreased level of high-density lipoproteins, silent myocardial ischemia on Holter monitoring, mitral and tricuspid valve prolapse, minor abnormalities of the heart were more frequent than in the advanced age group.
Conclusion:
There are age-related differences in the spectrum and frequency of risk factors in patients with first hemispheric ischemic stroke. This fact should be taken into account in stroke prevention programs in various age groups.
