Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Dendritic cells: clinical aspects.

R M Steinman1

  • 1Laboratory of Cellular Physiology and Immunology, Rockefeller University, New York, N.Y. 10021.

Research in Immunology
|November 1, 1989
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The cell surface of mouse lymphoid dendritic cells.

Immunology today·2014
Same author

Dendritic cell-targeted protein vaccines: a novel approach to induce T-cell immunity.

Journal of internal medicine·2011
Same author

The central nervous system in mucosal vaccination of rhesus macaques with simian immunodeficiency virus Deltanef.

Neuropathology and applied neurobiology·2007
Same author

Dendritic cells: translating innate to adaptive immunity.

Current topics in microbiology and immunology·2006
Same author

The dendritic cell advantage: New focus for immune-based therapies.

Drug news & perspectives·2003
Same author

The control of immunity and tolerance by dendritic cell.

Pathologie-biologie·2003
Same journal

The Macrophage in Human Pathology: Update on its Role in Induction of the Immune Response. Proceedings of the 1998 European Macrophage Conference. September 17-19, 1998.

Research in immunology·1999
Same journal

Protective T-cell responses against tumours.

Research in immunology·1999
Same journal

Pathogenic and protective responses in parasitic infections.

Research in immunology·1999
Same journal

Pathogenic and protective T-cell responses in autoimmune diseases.

Research in immunology·1999
Same journal

Th1 and Th2 cells.

Research in immunology·1999
Same journal

Antigen receptors in lymphoid cell development and lymphocyte activation.

Research in immunology·1999
See all related articles

Dendritic cells, crucial for immune responses, are increasingly understood in humans. Further research into dendritic cells holds promise for transplantation, immunity, autoimmunity, and HIV-1 infection.

Area of Science:

  • Immunology
  • Cell Biology

Background:

  • Clinical research on dendritic cells (DCs) is expanding.
  • Isolation and identification of human DCs are improving.
  • DCs play vital roles in antigen presentation and immune regulation.

Purpose of the Study:

  • To highlight the growing clinical relevance of dendritic cells.
  • To identify key areas for future dendritic cell research.
  • To underscore the potential of dendritic cells in various medical fields.

Main Methods:

  • Review and synthesis of current research on dendritic cell functions.
  • Identification of challenges and advancements in dendritic cell isolation and characterization.
  • Exploration of known and emerging dendritic cell properties.

Related Experiment Videos

Main Results:

  • Human dendritic cell isolation and identification methods are advancing.
  • Dendritic cells exhibit specialized antigen-presenting functions in humans, similar to other mammals.
  • New findings reveal dendritic cells' capacity to induce T-cell expansion and susceptibility to retroviral infection.

Conclusions:

  • Dendritic cell research is crucial for understanding human immunity.
  • Further investigation into dendritic cells is warranted for transplantation, T-cell immunity, autoimmunity, and HIV-1 infection.
  • Development of specific probes will accelerate dendritic cell research.