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Consequences of Correcting Intelligence Quotient for Prematurity at Age 5 Years

Sarit van Veen1, Cornelieke S H Aarnoudse-Moens1, Anton H van Kaam2

  • 1Psychosocial Department, Academic Medical Center, Amsterdam, The Netherlands; Department of Neonatology, Academic Medical Center, Amsterdam, The Netherlands.

The Journal of Pediatrics
|March 17, 2016
PubMed

Insights

Correcting for prematurity significantly increases IQ scores in very preterm children. These score differences varied based on gestational age and assessment timing, highlighting the need for standardized age correction methods.

Area of Science:

  • Neuropsychology
  • Developmental Pediatrics

Background:

  • Preterm birth can impact cognitive development.
  • Accurate assessment of cognitive abilities in preterm children is crucial for interventions.

Purpose of the Study:

  • To evaluate the effect of correcting for prematurity on cognitive scores (FSIQ, VIQ, PIQ, PSQ).
  • To examine factors associated with differences in corrected versus uncorrected IQ scores.

Main Methods:

  • A cohort of 275 very preterm children (GA <30 weeks) assessed at 5 years corrected age.
  • Comparison of IQ scores calculated using corrected versus uncorrected age.
  • Statistical analyses including paired t tests, repeated measures ANOVA, and ANCOVA.

Main Results:

  • All corrected IQ scores (FSIQ, VIQ, PIQ, PSQ) were significantly higher than uncorrected scores (P < .001).
  • Score differences ranged from 0-15 points and were larger for lower gestational ages and higher IQs.
  • Assessment timing relative to 3-month age bands also influenced score differences.

Conclusions:

  • There is substantial variation in IQ score differences when correcting for prematurity.
  • An international standard for appropriate age correction in cognitive assessments is recommended.
Abstract

Keywords:
Adjusted IQCognitionDevelopmentFollow-Up StudiesGestational AgePreterm Infant

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