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Published on: April 25, 2014
Changes in Acute Coronary Syndrome Treatment and Prognosis After Implementation of the Infarction Code in a Hospital
Alberto Cordero1, Ramón López-Palop1, Pilar Carrillo1
1Departamento de Cardiología, Hospital Universitario de San Juan, San Juan de Alicante, Alicante, Spain.
Insights
Implementing an infarction protocol improved acute coronary syndrome management, increasing ST-segment elevation rates and primary angioplasty use. High-risk patients saw reduced in-hospital mortality, with no change in long-term outcomes.
Area of Science:
- Cardiology
- Emergency Medicine
- Healthcare Systems
Background:
- Emergency care systems aim to optimize treatment for myocardial infarction and acute coronary syndrome.
- The impact of a dedicated infarction protocol on acute coronary syndrome (ACS) management requires evaluation.
Purpose of the Study:
- To compare the management and outcomes of patients with acute coronary syndrome before and after implementing a specific infarction protocol.
Main Methods:
- A comparative study analyzed 1210 patients admitted with ACS.
- Data collected included patient demographics, comorbidities, GRACE scores, treatment pathways, and in-hospital and post-discharge outcomes.
Main Results:
- Post-protocol implementation, there was a significant increase in ST-segment elevation ACS (29.8%-39.5%) and coronary revascularizations (82.1%-90.1%).
- Primary angioplasty became routine (51.9%-94.9%), with reduced catheterization times and increased early revascularization.
- Hospital stay shortened significantly, and in-hospital mortality decreased in high-risk patients (38.8%-22.4%).
Conclusions:
- The infarction protocol enhanced ACS care, evidenced by increased ST-segment elevation ACS and primary angioplasty rates.
- The protocol led to reduced hospital stays and improved in-hospital mortality for high-risk individuals.
- Long-term prognosis post-discharge remained consistent between the periods.
Introduction And Objectives:
Emergency care systems have been created to improve treatment and revascularization in myocardial infarction but they may also improve the management of all patients with acute coronary syndrome.
Methods:
A comparative study of all patients admitted with acute coronary syndrome before and after implementation of an infarction protocol.
Results:
The study included 1210 patients. While the mean age was the same in both periods, the patient group admitted after implementation of the protocol had a lower prevalence of diabetes mellitus and hypertension but more active smokers and higher GRACE scores. The percentage of ST-segment elevation acute coronary syndrome (29.8%-39.5%) and coronary revascularizations (82.1%-90.1%) significantly increased among patients admitted with acute coronary syndrome, and primary angioplasty became routine (51.9%-94.9%); there was also a reduction in time to catheterization and an increase in early revascularization. The mean hospital stay was significantly shorter after implementation of the infarction protocol. In-hospital mortality was unchanged, except in high-risk patients (38.8%-22.4%). After discharge, no differences were observed between the 2 periods in cardiovascular mortality, all-cause mortality, reinfarction, or major cardiovascular complications.
Conclusions:
After implementation of the infarction protocol, the percentage of patients admitted with ST-segment elevation acute coronary syndrome and the mean GRACE score increased among patients admitted with acute coronary syndrome. Hospital stay was reduced, and primary angioplasty use increased. In-hospital mortality was reduced in high-risk patients, and prognosis after discharge was the same in both periods.
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