Related Experiment Videos
[Thyroid autoimmunity in type I (insulin dependent) diabetes mellitus]
C Pavía Sesma1, C Valls Tolosa, B Eighian Baho
1Sección de Endocrinología, Hospital Infantil San Juan de Dios, Barcelona.
Anales Espanoles De Pediatria
|December 1, 1989
Summary
Screening for antithyroid antibodies is crucial in children with diabetes mellitus due to their high prevalence and association with chronic thyroiditis. Early detection enables timely intervention for thyroid dysfunction in pediatric diabetes patients.
Area of Science:
- Pediatric Endocrinology
- Immunology
- Metabolic Disorders
Context:
- Type 1 diabetes mellitus (T1DM) is an autoimmune disease.
- Children with T1DM have an increased risk of other autoimmune conditions.
- Thyroid dysfunction, particularly autoimmune thyroiditis, is a common comorbidity.
Purpose:
- To determine the prevalence of antithyroid antibodies in children with diabetes mellitus.
- To investigate the association between antithyroid antibodies and chronic thyroiditis in this population.
- To evaluate the clinical significance of screening for antithyroid antibodies in diabetic children.
Summary:
- A study screened 225 children (aged 4-18 years) with diabetes mellitus for antithyroid antibodies.
- Overall prevalence of thyroid antibodies was 14.19%, with 10.39% positive at diabetes onset.
- Chronic lymphocytic thyroiditis was diagnosed in 16 patients; thyroxine therapy was initiated for hypothyroid cases.
Impact:
- Highlights the significant prevalence of antithyroid antibodies in diabetic children.
- Supports routine screening for antithyroid antibodies in pediatric diabetes management.
- Emphasizes the link between diabetes and autoimmune thyroid disease, informing clinical practice.