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11:15
In Situ Detection of Bacteria within Paraffin-embedded Tissues Using a Digoxin-labeled DNA Probe Targeting 16S rRNA
Published on: May 21, 2015
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Microorganisms in periradicular tissues: Do they exist? A perennial controversy
Pooja Gupta Dudeja1, Krishan Kumar Dudeja2, Dhirendra Srivastava3
1Department of Conservative Dentistry, ESIC Dental College, New Delhi, India.
Journal of Oral and Maxillofacial Pathology : JOMFP
|March 17, 2016
Summary
Microbiology is central to endodontic practice, with most pulp and periradicular diseases stemming from microbial causes. Understanding this link is crucial for effective endodontic treatment strategies.
Area of Science:
- Endodontics
- Microbiology
- Immunology
Background:
- The practice of endodontics is intrinsically linked to microbiology.
- Many controversies in endodontics arise from a misunderstanding of the microbiological etiology of pulp and periradicular diseases.
- Microorganisms are the primary cause of most diseases affecting dental pulp and periradicular tissues.
Purpose of the Study:
- To elucidate the role of microorganisms in endodontic disease processes.
- To determine the reality of microbial presence in periradicular lesions.
- To bridge knowledge gaps concerning microbial involvement in endodontics.
Main Methods:
- An extensive electronic literature search was conducted.
- Databases used included PubMed and Google, with a search range of approximately 50 years.
- Inclusion/exclusion criteria were applied, and data from approximately 50 selected articles were extracted, pooled, and synthesized.
Main Results:
- The study synthesized data from relevant literature to address the role of microorganisms in endodontics.
- Evidence supports the significant involvement of microbes in the pathogenesis of endodontic diseases.
- The presence of microorganisms in periradicular lesions is a reality, not a myth.
Conclusions:
- A thorough understanding of the relationship between microorganisms and endodontic disease is essential.
- This understanding is fundamental for developing evidence-based treatment rationales in endodontics.
- Recognizing the microbiological basis of endodontic diseases improves treatment efficacy.
Keywords:
Anaerobic infectionsendodontic floramicroorganismsopen and closed root canalsperiradicular tissuesMore Related Videos
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