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Updated: Mar 24, 2026

Design of a Biocompatible Drug-Eluting Tracheal Stent in Mice with Laryngotracheal Stenosis
Published on: January 21, 2020
Subglottic tracheal stenosis
Antonio D'Andrilli1, Federico Venuta1, Erino Angelo Rendina1
11 Department of Thoracic Surgery, Sant'Andrea Hospital, Sapienza University, Rome, Italy ; 2 Department of Thoracic Surgery, Policlinico Umberto I, Sapienza University, Rome, Italy ; 3 Lorillard Spencer Cenci Foundation, Rome, Italy.
Abstract:
Benign subglottic stenosis represents a major therapeutic challenge. Interventional bronchoscopic treatment has a limited role in this setting due to anatomical and technical reasons. The benefit with these techniques is generally temporary, due to frequent recurrences, need for repeated procedures and risk of extending the area of damage. Laryngotracheal resection is at present the curative treatment of choice. Literature data show that surgical treatment may allow very high success rates at long term with low perioperative morbidity and mortality. Technical aspects and results are reported and discussed.
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