Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

In Vitro Fertilization

In Vitro Fertilization

In vitro fertilization (IVF) is a form of assisted reproductive technology where an egg is fertilized with sperm in a controlled laboratory environment before transferring the resulting embryo into the uterus. This process is designed to help individuals and couples experiencing difficulties conceiving.
The IVF process begins with ovarian stimulation, during which reproductive endocrinologists prescribe hormonal medications to stimulate the ovaries to produce multiple eggs instead of the single...

Infertility in Females

Infertility in Females

Female infertility is defined as the inability to conceive after a year of regular, unprotected intercourse and affects about 10–15% of couples worldwide. The primary cause of female infertility is ovulatory disorders, which hinder the release of eggs. These disorders can be classified as hypothalamic amenorrhea, polycystic ovarian syndrome (PCOS), premature ovarian failure, and hyperprolactinemic anovulation disorders.
Endometriosis, a condition characterized by abnormal growth of...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

A prospective experimental randomized controlled trial to investigate the effect of virtual reality (VR) technology on improving clinical pregnancy rates and lowering anxiety for IVF patients undergoing frozen embryo transfer (FET).

Journal of assisted reproduction and genetics·2026

Same author

The biology and clinical aspects of female infertility.

Systems biology in reproductive medicine·2026

Same author

A novel sperm FcR binding assay that assesses sperm fertilizing potential.

Systems biology in reproductive medicine·2025

Same author

Reproductive potential of abnormal embryos with whole and segmental chromosome aneuploidies diagnosed by next-generation sequencing based preimplantation genetic testing for aneuploidy.

Fertility and sterility·2025

Same author

Safety and effectiveness of office hysteroscopic metroplasty with and without uterine stent placement in infertile population: a 10-year retrospective study.

Therapeutic advances in reproductive health·2025

Same author

Cryopreserved sperm among patients with Oligoasthenoteratozoospermia.

European journal of obstetrics, gynecology, and reproductive biology·2024

Search research articles

Related Experiment Video

Updated: Mar 24, 2026

Author Spotlight: Multiplex Immunohistochemistry for Understanding Immune Regulation by Uterine NK Cells in Pregnancy

Author Spotlight: Multiplex Immunohistochemistry for Understanding Immune Regulation by Uterine NK Cells in Pregnancy

Published on: October 25, 2024

Recurrent implantation failure: a comprehensive review.

Khaled M Zohni¹, Itai Gat, Clifford Librach

¹CReATe Fertility Centre, Toronto, Canada - drlibrach@createivf.com.

Minerva Ginecologica

|March 17, 2016

Summary

Recurrent implantation failure (RIF) occurs after repeated embryo transfers fail. Understanding endometrial-embryonic interactions and embryonic development is key to developing new RIF diagnostics and therapies.

More Related Videos

Multiplexed Fluorescent Immunohistochemical Staining of Four Endometrial Immune Cell Types in Recurrent Miscarriage

Multiplexed Fluorescent Immunohistochemical Staining of Four Endometrial Immune Cell Types in Recurrent Miscarriage

Published on: August 4, 2021

Author Spotlight: Advancing Therapeutic Strategies for Improving Pregnancy Rates by Analyzing Embryo-Endometrium Interactions

Author Spotlight: Advancing Therapeutic Strategies for Improving Pregnancy Rates by Analyzing Embryo-Endometrium Interactions

Published on: June 21, 2024

Related Experiment Videos

Last Updated: Mar 24, 2026

Author Spotlight: Multiplex Immunohistochemistry for Understanding Immune Regulation by Uterine NK Cells in Pregnancy

Author Spotlight: Multiplex Immunohistochemistry for Understanding Immune Regulation by Uterine NK Cells in Pregnancy

Published on: October 25, 2024

Multiplexed Fluorescent Immunohistochemical Staining of Four Endometrial Immune Cell Types in Recurrent Miscarriage

Multiplexed Fluorescent Immunohistochemical Staining of Four Endometrial Immune Cell Types in Recurrent Miscarriage

Published on: August 4, 2021

Author Spotlight: Advancing Therapeutic Strategies for Improving Pregnancy Rates by Analyzing Embryo-Endometrium Interactions

Author Spotlight: Advancing Therapeutic Strategies for Improving Pregnancy Rates by Analyzing Embryo-Endometrium Interactions

Published on: June 21, 2024

Area of Science:

Reproductive biology
Embryology
Genetics

Background:

Successful pregnancy requires synchronized embryo-maternal communication.
Recurrent implantation failure (RIF) is defined as repeated failed embryo transfers into a receptive uterus.
The causes of RIF can involve the embryo, maternal factors, or both, but remain incompletely understood.

Purpose of the Study:

To provide a comprehensive review of current knowledge on recurrent implantation failure.
To highlight the importance of endometrial-embryonic interactions in successful implantation.
To discuss the role of molecular technologies in advancing RIF research.

Main Methods:

Review of existing literature on implantation, RIF, and related molecular mechanisms.
Analysis of current research trends in reproductive science and genetics.
Synthesis of information on embryonic development and endometrial receptivity.

Main Results:

Implantation is a complex process dependent on precise cross-talk between the embryo and endometrium.
Limited understanding persists regarding the specific molecular causes of RIF.
Advancements in molecular technologies are crucial for elucidating RIF mechanisms.

Conclusions:

Further research into endometrial-embryonic molecular interactions is essential for RIF.
Preimplantation genetic evaluation and understanding embryonic development are vital areas of study.
New diagnostic and therapeutic strategies for RIF are anticipated with evolving molecular insights.