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Personalizing IBD Therapy: The Asian Perspective.

Suk-Kyun Yang1

  • 1Department of Gastroenterology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.

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This summary is machine-generated.

Personalized therapy for inflammatory bowel disease (IBD) aims to improve outcomes by tailoring treatments. This review focuses on personalized IBD therapy from an Asian perspective, considering unique patient characteristics and healthcare systems.

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Area of Science:

  • Gastroenterology and Immunology
  • Personalized Medicine
  • Inflammatory Bowel Disease (IBD) Research

Background:

  • Inflammatory bowel disease (IBD) patients have diverse clinical features, necessitating individualized treatment approaches.
  • Therapeutic goals for IBD include mucosal healing and improved long-term outcomes, but patient variability impacts treatment selection.
  • Treatment options range from no therapy to combination therapies like anti-TNF agents and immunosuppressants.

Purpose of the Study:

  • To review the current progress in personalized inflammatory bowel disease (IBD) therapy.
  • To discuss the application of personalized IBD therapy specifically from the Asian perspective.
  • To highlight differences in IBD patient characteristics and treatment responses between Asian and Western populations.

Main Methods:

  • Literature review of current personalized IBD therapy strategies.
  • Analysis of clinical characteristics, therapeutic responses, and prognoses of IBD patients in Asian populations.
  • Comparison of personalized IBD therapy approaches in Asian versus Western contexts.

Main Results:

  • Personalized IBD therapy involves predicting clinical course and treatment response, followed by therapeutic adjustments.
  • Asian IBD patients exhibit distinct clinical characteristics, treatment responses, and prognoses compared to Western patients.
  • Environmental, genetic, healthcare, and sociocultural factors influence personalized IBD therapy in Asia.

Conclusions:

  • Personalizing IBD therapy can maximize efficacy, minimize adverse events, and reduce healthcare costs.
  • Tailoring IBD treatment to individual patient profiles is crucial for optimal management.
  • Personalized IBD therapy strategies may need adaptation for Asian populations due to unique factors.