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Phaeohyphomycosis in renal transplantation: report of two cases

Walmar Roncalli Pereira de Oliveira1, Maria Fernanda Longo Borsato1, Maria Luiza Ducati Dabronzo1

  • 1Universidade de São Paulo, São Paulo, SP, Brazil.

Anais Brasileiros De Dermatologia
|March 17, 2016
PubMed

Insights

Phaeohyphomycosis, a fungal infection caused by melanin-containing fungi like Exophiala sp., presents varied clinical symptoms. This opportunistic infection poses diagnostic and therapeutic challenges, particularly in kidney transplant recipients.

Area of Science:

  • Mycology
  • Infectious Diseases
  • Immunocompromised Host Research

Background:

  • Phaeohyphomycosis is a fungal infection characterized by melanin in the fungal cell wall.
  • It is caused by various pigmented filamentous fungi.
  • Opportunistic infections are a growing concern in immunocompromised individuals.

Observation:

  • Two cases of phaeohyphomycosis caused by Exophiala sp. are presented.
  • The clinical presentation of the infection exhibited significant variability.
  • Patients were kidney transplant recipients, indicating an immunocompromised state.

Findings:

  • Exophiala sp. can cause phaeohyphomycosis with diverse clinical manifestations.
  • Diagnostic approaches for phaeohyphomycosis can be challenging.
  • Therapeutic strategies for this infection require careful consideration in transplant patients.

Implications:

  • Highlights the clinical variability of phaeohyphomycosis, underscoring the need for broad diagnostic considerations.
  • Emphasizes the diagnostic and therapeutic difficulties of opportunistic fungal infections in immunosuppressed patients.
  • Informs clinical practice regarding the management of Exophiala sp. infections in kidney transplant recipients.

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