Myxofibrosarcoma - Case report
Breno Augusto Campos de Castro1, André Costa Cruz Piancastelli1, Renata Leal Bregunci Meyer2
1Hospital da Polícia Militar de Minas Gerais, Belo Horizonte, MG, Brazil.
Anais Brasileiros De Dermatologia
|March 17, 2016
Summary
Myxofibrosarcoma, a rare cancer, often affects the elderly and can be aggressive. This case highlights diagnostic challenges in older patients with this soft tissue tumor.
Area of Science:
- Oncology
- Pathology
- Dermatology
Background:
- Myxofibrosarcoma is a malignant soft tissue tumor of fibroblastic origin.
- It predominantly affects the elderly, often presenting as nodules or tumors on the lower limbs.
- Histological features include spindle cell proliferation within a myxoid stroma.
Observation:
- The study presents a case of an 84-year-old patient.
- The tumor exhibited characteristics of a highly aggressive neoplasm.
- Diagnosis proved challenging in this elderly individual.
Findings:
- Myxofibrosarcoma demonstrates a high propensity for local recurrence and metastasis.
- Higher histological grades (intermediate or high) correlate with increased risk of recurrence and metastasis.
- The aggressive nature of the tumor in this case underscores the importance of timely diagnosis.
Implications:
- Early and accurate diagnosis of myxofibrosarcoma is crucial for effective management.
- Understanding the histological grade aids in predicting prognosis and treatment strategies.
- This case emphasizes the need for vigilance in diagnosing rare and aggressive tumors in the elderly.


