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Isolation of Primary Human Proximal Tubule Epithelial Cells and Their Use in Creating a Microphysiological Model of the Renal Proximal Tubule
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Proximal Junctional Kyphosis.

Han Jo Kim1, Sravisht Iyer

  • 1From the Hospital for Special Surgery, New York, NY.

The Journal of the American Academy of Orthopaedic Surgeons
|March 17, 2016
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Summary
This summary is machine-generated.

Proximal junctional kyphosis (PJK) after spinal surgery presents a spectrum of severity. Further research is needed to define proximal junctional failure for better patient stratification and study.

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Area of Science:

  • Orthopedics
  • Neurosurgery
  • Spinal Surgery

Background:

  • Proximal junctional kyphosis (PJK) is a frequent complication after adult spinal deformity surgery.
  • PJK is characterized by specific radiographic criteria and multifactorial causes including surgical, radiographic, and patient-related factors.
  • The clinical presentation of PJK ranges from asymptomatic deformity to severe pain and neurological deficits.

Purpose of the Study:

  • To highlight the broad spectrum of Proximal Junctional Kyphosis (PJK) following adult spinal deformity surgery.
  • To emphasize the need for improved classification schemes to stratify PJK severity.
  • To underscore the necessity of a consensus definition for proximal junctional failure.

Main Methods:

  • Review of existing literature on Proximal Junctional Kyphosis (PJK) following adult spinal deformity surgery.
  • Analysis of diagnostic criteria and clinical presentations of PJK.
  • Discussion of the spectrum of PJK, including proximal junctional failure.

Main Results:

  • Proximal junctional kyphosis (PJK) is defined by specific sagittal Cobb angle measurements.
  • PJK has diverse etiologies and a wide range of clinical manifestations.
  • Increased pain is a noted symptom in some PJK patients.

Conclusions:

  • A need exists for refined classification systems for Proximal Junctional Kyphosis (PJK).
  • A uniform definition of proximal junctional failure is essential for systematic research.
  • Standardized definitions will aid in understanding and managing PJK severity and outcomes.