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Updated: Aug 18, 2026

Comparative Analysis of Human Growth Hormone in Serum Using SPRi, Nano-SPRi and ELISA Assays
Published on: January 7, 2016
Oral clonidine: an effective growth hormone provocative test
Abstract:
Twenty normal statured healthy children (8 M; 12 F) aged 9-16 years were subjected to growth hormone (GH) provocative tests. The mean basal GH level was 2.0 +/- 0.42 ng/ml (+/- SEM). The mean peak levels of GH were 11.9 +/- 2.19 ng/ml (+/- SEM) after exercise, 9.82 +/- 2.81 ng/ml (+/- SEM) after insulin and 15.2 +/- 2.54 ng/ml (+/- SEM) after oral clonidine. A significant rise (peak level greater than 7 ng/ml) of serum GH was found in 70, 80 and 85% of children after exercise, insulin and oral clonidine tests, respectively. The observation in the present study indicates that oral clonidine test, a safer, easier and more economical test than insulin hypoglycemia, is equally potent and can be done in out patients.
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