Related Experiment Video
Updated: Mar 24, 2026

Establishment of a High-throughput Setup for Screening Small Molecules That Modulate c-di-GMP Signaling in Pseudomonas aeruginosa
Published on: June 30, 2016
A Universal Culture Medium for Screening Polymyxin-Resistant Gram-Negative Isolates
Patrice Nordmann1, Aurélie Jayol2, Laurent Poirel2
1Emerging Antibiotic Resistance Unit, Medical and Molecular Microbiology, Department of Medicine, Faculty of Science, University of Fribourg, Fribourg, Switzerland HFR, Hôpital Cantonal, Fribourg, Switzerland patrice.nordmann@unifr.ch.
Abstract:
The colistin-containing SuperPolymyxin medium was developed for screening polymyxin-resistant Gram-negative bacteria. It was evaluated with 88 polymyxin-susceptible or polymyxin-resistant cultured Gram-negative isolates. Its sensitivity and specificity of detection were ca. 100%. The SuperPolymyxin medium is the first screening medium that is able to detect intrinsic and acquired polymyxin-resistant bacteria.

