Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Control of oral anticoagulation. Current concepts].

C A Aguilar, R Hurtado Monroy, J Gaspar Hernández

    Revista De Investigacion Clinica; Organo Del Hospital De Enfermedades De La Nutricion
    |October 1, 1989
    PubMed
    Summary

    Standardizing prothrombin time (PT) testing is crucial for monitoring oral anticoagulation. The World Health Organization (WHO) recommends the International Normalized Ratio (INR) for accurate and safe patient management.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Nascent extracellular matrix converts biomaterial cues into cell fate decisions.

    bioRxiv : the preprint server for biology·2026
    Same author

    Validation of the German revised Addenbrooke's cognitive examination for detecting mild cognitive impairment, mild dementia in alzheimer's disease and frontotemporal lobar degeneration.

    Dementia and geriatric cognitive disorders·2010
    Same author

    [The benefit of a coronary stent in the reduction of major cardiac complications in acute coronary syndromes].

    Archivos del Instituto de Cardiologia de Mexico·1999
    Same author

    The apolipoprotein E4 allele is not associated with an abnormal lipid profile in a Native American population following its traditional lifestyle.

    Atherosclerosis·1999
    Same author

    [Coronary stent in acute myocardial infarction].

    Archivos del Instituto de Cardiologia de Mexico·1998
    Same author

    [Coronary stents. Results during the hospitalization phase].

    Archivos del Instituto de Cardiologia de Mexico·1997

    Area of Science:

    • Hematology
    • Clinical Chemistry

    Context:

    • Oral anticoagulant therapy requires reliable monitoring of blood clotting.
    • Variability in prothrombin time (PT) testing methods and reagents affects therapeutic range accuracy.

    Purpose:

    • To review recent advances in prothrombin time (PT) standardization.
    • To analyze World Health Organization (WHO) recommendations for oral anticoagulant monitoring.

    Summary:

    • The prothrombin time (PT) measures the effectiveness of oral anticoagulants.
    • The WHO recommends the International Normalized Ratio (INR) for PT results, calculated using the thromboplastin's International Sensitivity Index (ISI).
    • INR standardization ensures consistent and comparable PT results across different laboratories and reagents.

    Related Experiment Videos

    Impact:

    • Implementation of WHO recommendations can improve the safety and effectiveness of oral anticoagulation therapy.
    • Standardized PT testing via INR enhances patient care and reduces risks associated with anticoagulant treatment.
    • Promotes consistent laboratory and clinical practice for managing thrombotic disorders.