Related Experiment Video
Updated: Mar 24, 2026
04:50
Preliminary Study on Acupuncture Combined with Grain-sized Moxibustion for Treating Rheumatoid Arthritis with Finger Joint Pain
Published on: May 16, 2025
1.3K
Vaccinations for rheumatoid arthritis
Marcia A Friedman1, Kevin Winthrop
1aDepartment of Rheumatology bDepartment of Infectious Diseases, Oregon Health and Science University, Portland, Oregon, USA.
Current Opinion in Rheumatology
|March 18, 2016
Summary
Vaccinations are crucial for rheumatoid arthritis (RA) patients, but drug therapies can impact effectiveness. This review guides optimal vaccine use and timing for RA care.
Area of Science:
- Rheumatology
- Immunology
- Infectious Diseases
Background:
- Rheumatoid arthritis (RA) patients face higher risks of infectious diseases.
- Disease-modifying antirheumatic drug (DMARD) therapy can affect vaccine immunogenicity.
- Vaccine selection and timing are critical considerations in RA management.
Purpose of the Study:
- To review current indications for vaccines in RA patients.
- To assess the safety and immunogenicity of vaccines in RA.
- To provide guidance on optimal vaccine use and timing for rheumatologists.
Main Methods:
- Literature review of recent recommendations and studies.
- Analysis of vaccine indications, safety, and immunogenicity data.
- Synthesis of evidence regarding vaccine effectiveness in RA patients on DMARDs.
Main Results:
- Influenza, pneumococcal, and shingles vaccines are recommended for RA patients.
- These vaccines are generally safe and immunogenic, except with rituximab therapy.
- Hepatitis B and HPV vaccines are also well-tolerated and immunogenic.
- Live vaccines (shingles, yellow fever) may be safe in select RA patients.
Conclusions:
- Optimal use and timing of routine vaccinations are essential for RA patient care.
- This review provides updated guidance for rheumatologists.
- Vaccination strategies should be tailored to individual RA patient needs and therapies.
Related Concept Videos
01:21Rheumatic Heart Disease III: Medical Management
484
Rheumatic heart disease (RHD) management can be divided into two main strategies: prevention and long-term management.Primary PreventionPrimary prevention focuses on timely diagnosis and management of group A streptococcal pharyngitis to prevent acute rheumatic fever. The most widely used antibiotic for treating this condition is intramuscular benzathine penicillin G.Acute Rheumatic Fever TreatmentThe primary treatment goal for a patient diagnosed with acute rheumatic fever is to suppress the...
484
01:51Vaccinations
53.5K
Overview
53.5K
01:20Rheumatic Heart Disease IV: Nursing Management
441
AssessmentA comprehensive assessment is essential in managing a patient with rheumatic heart disease (RHD). Begin with obtaining a detailed medical history, including recent streptococcal infections, a history of rheumatic fever, or previously diagnosed rheumatic heart disease. Assess the patient for symptoms such as fever, chest pain, widespread joint pain (arthralgia), tachycardia, pericardial friction rub, muffled heart sounds, heart murmurs, peripheral edema, subcutaneous nodules, and...
441
01:23Rheumatic Heart Disease I: Introduction
821
Rheumatic heart disease or RHD is a chronic condition that results from rheumatic fever, causing permanent damage to the heart valves.Etiology and Risk FactorsIt primarily arises from rheumatic fever, an inflammatory disease that can develop after untreated or inadequately treated group A streptococcal (GAS) pharyngitis. Streptococcus spreads through direct contact with oral or respiratory secretions. While the bacteria are the causative agents, factors like malnutrition, overcrowding, poor...
821
01:11Genome-wide Association Studies-GWAS
16.6K
Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...
GWAS does not require the identification of the target gene involved in...
16.6K
01:22Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies
970
The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...
970