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Generation of a Rat Model of Acute Liver Failure by Combining 70% Partial Hepatectomy and Acetaminophen
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A Novel Resolvin-Based Strategy for Limiting Acetaminophen Hepatotoxicity

Suraj J Patel1,2, Jay Luther3, Stefan Bohr1

  • 1Center for Engineering in Medicine and the Department of Surgery, Massachusetts General Hospital and the Shriners Burns Hospital, Boston, MA, USA.

Clinical and Translational Gastroenterology
|March 18, 2016
PubMed
Summary

Resolvins offer a promising new treatment for acetaminophen (APAP)-induced liver injury, outperforming N-acetyl cysteine (NAC) by extending the therapeutic window and reducing inflammation.

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