An Overview of the Diagnosis and Management of Eosinophilic Esophagitis
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Updated: Mar 24, 2026

Author Spotlight: Investigating the Pathophysiology of Eosinophilic Esophagitis
Published on: May 10, 2024
Manish B Singla1, Fouad J Moawad1
1Gastroenterology Division, Department of Internal Medicine, Walter Reed National Military Medical Center, Bethesda, Maryland, USA.
Abstract:
Eosinophilic esophagitis (EoE) is a chronic inflammatory condition characterized by symptoms of esophageal dysfunction and eosinophilic infiltration of the esophageal mucosa. The diagnosis requires esophageal biopsies demonstrating at least 15 eosinophils per high-powered field following a course of high-dose proton pump inhibitors. Management of EoE consists of the three Ds: drugs, dietary therapy, and esophageal dilation. In this review, we discuss the epidemiology, pathogenesis, diagnosis, and treatment of EoE to include the role of emerging therapies.
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