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A new desensitizing dentifrice: preliminary report.
Journal of the American Dental Association (1939)
|November 1, 1977
Summary
A pluronic polyol gel with sodium citrate effectively reduced tooth dentin sensitivity in a six-week clinical trial. Other tested toothpastes, including strontium chloride and stannous fluoride, showed no significant improvement over the control.
Area of Science:
- Dentistry
- Dental Therapeutics
Background:
- Dentin hypersensitivity is a common and challenging dental issue.
- Effective treatments for dentin sensitivity are limited.
Observation:
- A clinical trial evaluated five dentifrices for sensitivity reduction over six weeks.
- 176 adults with 486 hypersensitive tooth surfaces participated.
- Participants used strontium chloride, stannous fluoride, pluronic F-127-sodium citrate, pluronic F-127, or a control dentifrice.
Findings:
- The pluronic F-127 gel with sodium citrate demonstrated highly significant desensitizing effects.
- The plain pluronic F-127 gel showed a lesser degree of effectiveness.
- Strontium chloride and stannous fluoride dentifrices did not significantly outperform the control.
Implications:
- A pluronic polyol gel containing sodium citrate is a highly effective agent for managing tooth hypersensitivity.
- This formulation offers a promising new therapeutic option for dentin sensitivity.
- Further research may explore optimal application and long-term efficacy.