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Nano-biomaterials for cardiovascular applications: Clinical perspective
Iwona Cicha1, Raminder Singh1, Christoph D Garlichs2
1Cardiovascular Nanomedicine Unit, Section of Experimental Oncology and Nanomedicine, ENT-Department, University Hospital Erlangen, Germany.
Summary
Biomaterials offer promising solutions for cardiovascular diseases, a leading cause of death. This review highlights their potential in novel therapeutic and regenerative cardiovascular applications.
Area of Science:
- Biomaterials Science
- Cardiovascular Medicine
- Nanotechnology
Background:
- Cardiovascular diseases (CVDs) cause approximately 25% of global deaths and are increasing worldwide.
- Despite advances in diagnostics and therapy, effective treatments remain a challenge.
- Biomaterials offer advantages over synthetic materials for therapeutic and regenerative purposes.
Purpose of the Study:
- To review scientific literature on (nano)biomaterials for cardiovascular applications.
- To identify promising materials for improving existing therapies and developing novel constructs.
- To focus on the clinical relevance and potential of these biomaterials.
Main Methods:
- Systematic literature review of scientific reports.
- Focus on (nano)biomaterials relevant to cardiovascular diseases.
- Analysis of therapeutic, regenerative, and drug delivery applications.
Main Results:
- Biomaterials show potential as drug carriers and protective nanoshells.
- Nanoformulations enhance biocompatibility of imaging agents.
- Numerous promising (nano)biomaterials are being investigated for cardiovascular applications.
Conclusions:
- Biomaterials, particularly in nanoformulations, present significant opportunities for cardiovascular disease treatment and regeneration.
- Further research into novel biomaterial constructs can lead to improved cardiovascular care.
- The clinical translation of these advanced materials is a key future direction.
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