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Photodistributed granuloma annulare.

Julia Gittler1, Adnan Mir, Shane A Meehan

  • 1New York University School of Medicine.

Dermatology Online Journal
|March 19, 2016
PubMed
Summary

Annular elastolytic giant cell granuloma (AEGCG) may be a variant of granuloma annulare (GA). This case highlights the association between AEGCG, diabetes mellitus, and photodistributed skin lesions.

Area of Science:

  • Dermatology
  • Pathology

Background:

  • Annular elastolytic giant cell granuloma (AEGCG) is a debated dermatological condition, often considered a variant of granuloma annulare (GA).
  • AEGCG predominantly affects Caucasian women aged 40-70, with lesions typically on sun-exposed skin.

Observation:

  • A 52-year-old woman presented with a two-year history of asymptomatic, annular, erythematous, photodistributed skin eruption.
  • Her evaluation revealed a Hemoglobin A1C of 10.3%, leading to a diagnosis of diabetes mellitus.

Findings:

  • The case illustrates a potential link between AEGCG and diabetes mellitus.
  • Clinical and histopathologic features of GA and AEGCG show significant overlap, supporting the view of AEGCG as a GA variant.

Implications:

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  • This case underscores the importance of considering systemic associations, such as diabetes mellitus, in patients with AEGCG.
  • Further research into the relationship between granuloma annulare variants and metabolic disorders is warranted.