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Related Experiment Video

Updated: Mar 24, 2026

Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration

Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration

Published on: May 26, 2023

Primary diffuse macular amyloidosis.

Melissa Kanchanapoomi¹, Rachel Rosenstein, Marianna Shvartsbeyn

¹New York University School of Medicine.

Dermatology Online Journal

|March 19, 2016

Summary

This summary is machine-generated.

This case study details a 53-year-old woman diagnosed with diffuse macular amyloidosis. It explores the clinical signs, underlying causes, and related conditions of this skin disorder.

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Last Updated: Mar 24, 2026

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Published on: May 26, 2023

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Area of Science:

Dermatology
Pathophysiology
Clinical Medicine

Background:

Cutaneous macular amyloidosis (CMA) is a pigmentary disorder characterized by reticulated hyperpigmentation.
It primarily affects the upper back and neck, but can present diffusely.

Observation:

A 53-year-old woman presented with diffuse macular amyloidosis, extending beyond typical areas.
The patient's clinical presentation included characteristic reticulated hyperpigmentation.

Findings:

The case highlights the varied clinical manifestations of cutaneous macular amyloidosis.
Discussion includes potential pathophysiologic mechanisms and associated conditions.
Amyloid deposition in the skin is a key feature.

Implications:

Understanding diffuse presentations of CMA is crucial for accurate diagnosis.
Further research into pathophysiologic mechanisms may reveal novel therapeutic targets.
Recognizing associations can aid in comprehensive patient management.